Pollen, specifically rye grass pollen extract (Secale cereale), has been used to support prostate health, particularly for alleviating symptoms of benign prostatic hyperplasia (BPH). Several clinical studies, primarily conducted in Europe and Japan, have investigated its effectiveness. Systematic reviews and meta-analyses, such as those published by the Cochrane Collaboration, suggest that pollen extracts may modestly improve urinary symptoms associated with BPH, including increased flow rate and decreased residual urine volume. The mechanism of action is not fully understood but may involve anti-inflammatory properties and inhibition of prostate growth factors.

Despite positive findings in some trials, the overall quality of evidence is considered moderate due to issues such as small sample sizes, short duration, and methodological limitations in many studies. Major urological associations do not universally recommend pollen extract as first-line therapy, but it is recognized as a potential adjunct or alternative for men seeking non-pharmaceutical options, particularly in regions where it has been traditionally used.

In summary, there is scientific evidence, though not robust, supporting the use of pollen extract for prostate health, particularly for mild to moderate BPH symptoms. Continued research with larger, well-designed clinical trials is needed to clarify its efficacy and safety profile.