Evidence supporting the use of: Nettle (mixed)
For the body system: Prostate
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Nettle (Urtica dioica), particularly the root, has been studied for its effects on the prostate, especially in relation to benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate gland that affects many aging men. Several clinical trials and systematic reviews suggest that nettle root extracts can help alleviate lower urinary tract symptoms associated with BPH. The proposed mechanisms include inhibition of sex hormone-binding globulin, effects on inflammatory pathways, and possible inhibition of enzymes involved in prostate growth (such as aromatase and 5-alpha-reductase).
For example, a randomized, double-blind study published in Journal of Herbal Pharmacotherapy (2005) found that nettle root extract significantly improved symptoms of BPH compared to placebo. Other meta-analyses have concluded that while the evidence is not as robust as for pharmaceutical treatments (like alpha-blockers), nettle shows promise as a complementary or alternative option with a favorable safety profile.
It is crucial to note that most studies have focused specifically on nettle root, not the leaf or other plant parts, and that while the evidence supports symptom relief, there is less evidence for direct effects on prostate size. More large-scale, high-quality studies are needed, but the current scientific evidence does support the use of nettle root for supporting prostate health, warranting a moderate evidence rating.
Other ingredients that support Prostate
7-hydroxymatairesinol (HMR)beta-sitosterol
sesame
boron
broccoli
campesterol
turmeric
diallyl trisulfide (DATS)
DIM (diindolylmethane)
epigallocatechin gallate (EGCG)
flaxseed
gamma tocopherol
genistein
gokhru
green tea
HMR lignan
indole-3-carbinol
lignans
lycopene
mixed carotenoids
nettle
parsley
phytosterols
plant sterols
pollen
pomegranate
pumpkin
pygeum
quercetin
saw palmetto
secoisolariciresinol diglucoside
selenium
soybean
sterols
stigmasterol
tomato
vitamin D
watermelon
zinc
bee pollen
lingzhi
Equol (proprietary)
hydrangea
herbal blend (proprietary)
Apigenin
Alchornea
Alpha phytosterol
Allium tuberosum
Anti-aromatase
Brassica
berry
Brazil nut
Ba Ji Tian
Bee products
Borassus aethiopum
Chinese Mountain Ant
Cucurbita
Cynomorium
Cruciferous
Crinum latifolium
Decursin
Daidzein
Dwarf Nettle
Ellagic Acid
Garlic
Isoflavones
Soy Protein
walnut
Other body systems supported by Nettle (mixed)
Adrenal GlandsArteries
Bladder
Blood
Circulatory System
Digestive System
Gastrointestinal Tract
Glandular System
Hair
Immune System
Intestinal System
Joints
Kidneys
Liver
Lungs
Lymphatics
Male Reproductive System
Muscles
Nails
Prostate
Reproductive System
Respiratory System
Skin
Urinary System