Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Diallyl trisulfide (DATS) is a sulfur-containing compound derived from garlic (Allium sativum) that has been investigated for its potential health benefits, including effects on the prostate. Most of the research concerning DATS and prostate health is preclinical, focusing on its anti-cancer properties, particularly with respect to prostate cancer. Laboratory and animal studies have shown that DATS can induce apoptosis (programmed cell death) and inhibit the proliferation of prostate cancer cells. For example, studies published in peer-reviewed journals such as Cancer Research and Carcinogenesis have demonstrated that DATS can suppress tumor growth, modulate cell cycle regulatory proteins, and inhibit angiogenesis in prostate cancer models.

However, clinical evidence in humans is currently lacking. There are no well-conducted randomized controlled trials that directly evaluate the effect of DATS supplementation on prostate health or prostate cancer in humans. The use of garlic and its extracts for general health, including prostate support, does have traditional roots, but the specific use of DATS for this purpose is based on promising—but still preliminary—scientific findings. Therefore, while there is a scientific rationale for its investigation, the evidence supporting DATS for prostate support is limited and primarily preclinical at this time.

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