Evidence supporting the use of: Boron
For the body system: Prostate

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Boron is a trace mineral that has been investigated for its potential role in supporting prostate health, particularly in relation to prostate cancer risk and testosterone metabolism. Some scientific studies suggest that boron may influence the metabolism of sex hormones, including testosterone and estradiol, which are relevant to prostate function. For example, small human studies have shown that boron supplementation can increase free testosterone levels and decrease estradiol, factors that could potentially impact prostate health. Furthermore, laboratory studies (in vitro and in vivo) have found that boron can inhibit the growth of prostate cancer cells, possibly by affecting enzymes involved in cell proliferation and apoptosis.

However, clinical evidence in humans regarding boron's effect on prostate health is limited and not definitive. Most available data come from animal research, cell studies, or small human trials with surrogate endpoints (like hormone levels), rather than large, well-controlled clinical trials demonstrating a direct effect on prostate disease outcomes. Epidemiological studies have suggested that dietary boron intake may be inversely associated with prostate cancer risk, but these findings are not sufficiently robust to establish causality. Thus, while there is a scientific rationale and some preliminary evidence for boron's role in supporting prostate health, high-quality human studies are lacking.

In summary, boron's use for prostate support is based on biological plausibility and early research, but the overall quality and quantity of evidence are low, meriting a rating of 2 out of 5.

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