Evidence supporting the use of: Vitamin B6
For the health condition: Pregnancy (herbs and supplements for)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin B6 (pyridoxine) is scientifically validated for use during pregnancy, particularly for the management of nausea and vomiting, commonly known as "morning sickness." Multiple randomized controlled trials and systematic reviews have demonstrated that vitamin B6 supplementation can significantly reduce the severity of nausea in pregnant women, especially during the first trimester. It is often recommended as a first-line therapy for mild to moderate pregnancy-related nausea before more potent antiemetic medications are considered.

The mechanism by which vitamin B6 alleviates nausea is not fully understood, but it is thought to be connected to its role in neurotransmitter synthesis and regulation. The American College of Obstetricians and Gynecologists (ACOG) and other medical bodies endorse the use of vitamin B6 for this purpose, typically at doses of 10-25 mg three times daily. Furthermore, vitamin B6 is sometimes combined with doxylamine (an antihistamine) for added effectiveness, a combination that is considered safe in pregnancy.

Beyond nausea, vitamin B6 is essential for fetal brain development and the metabolism of proteins, carbohydrates, and fats. However, routine supplementation beyond the recommended dietary allowance is not necessary unless treating specific symptoms such as morning sickness. Overall, the use of vitamin B6 for pregnancy nausea is well-supported by scientific evidence, earning it a high evidence rating.

More about vitamin B6
More about Pregnancy (herbs and supplements for)

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