Evidence supporting the use of: DHA (docosahexaeonic acid)
For the health condition: Post Partum Depression

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

DHA (docosahexaenoic acid) is an omega-3 fatty acid found predominantly in fish oils and is a critical component of brain and neuronal membranes. Its use in supporting or treating postpartum depression (PPD) is primarily justified by scientific investigation, although the evidence is mixed and not definitive. Several observational studies have noted that lower levels of DHA during pregnancy and postpartum are associated with higher risks of depressive symptoms. The biological rationale is that DHA is essential for optimal brain function, and pregnancy substantially depletes maternal DHA stores, potentially increasing vulnerability to mood disorders. Randomized controlled trials (RCTs) and systematic reviews have evaluated DHA supplementation for preventing or treating PPD, but the results have been inconsistent. Some trials have found modest reductions in depressive symptoms with supplementation, while others have found no significant effect compared to placebo. A 2018 Cochrane review concluded that there is insufficient evidence to recommend omega-3 supplementation, including DHA, for the prevention or treatment of PPD. Possible reasons for inconsistent findings include variations in dose, baseline dietary intake, and the timing of supplementation. Despite the lack of robust evidence, DHA supplementation is sometimes recommended by healthcare practitioners due to its safety profile and other health benefits for mother and infant. Overall, while there is a scientific rationale and some supporting data, the quality and consistency of evidence supporting DHA for PPD is limited.

More about DHA (docosahexaeonic acid)
More about Post Partum Depression