Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Synopsis: Omega-3 fatty acids have some scientific backing for their use in alleviating symptoms of premenstrual syndrome (PMS), including PMS Type D, which is characterized by depressive symptoms such as mood swings, irritability, and sadness. Several clinical studies have investigated the effect of omega-3 supplementation—primarily eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)—on mood-related PMS symptoms. For example, a double-blind, randomized controlled trial published in Reproductive Health (2013) found that women who took 2 grams of omega-3 daily for two months experienced significant reductions in depression, anxiety, and bloating compared to placebo. The proposed mechanisms include omega-3’s ability to modulate neurotransmitter function (especially serotonin and dopamine), reduce neuroinflammation, and improve neuronal membrane fluidity, all of which may contribute to improved mood and cognitive function.

Meta-analyses have generally supported a moderate benefit, though not all studies have found significant effects, and the quality of evidence varies. Overall, there is enough clinical data to suggest that omega-3 fatty acids may be a beneficial adjunct therapy for PMS Type D, especially for women who prefer non-pharmacological approaches. However, the evidence is not robust enough to warrant a maximum score, as more large-scale, high-quality trials are needed to confirm these findings and to determine optimal dosing strategies.

More about omega-3 fatty acids
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Other ingredients used for PMS Type D

Other health conditions supported by omega-3 fatty acids

Products containing omega-3 fatty acids

Nature's Sunshine Flax Seed Oil (With Lignans)