Evidence supporting the use of: Calcium
For the health condition: PMS Type D

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Calcium is scientifically validated as a supportive treatment for PMS Type D (Depression), which is characterized by mood-related symptoms such as depression, tearfulness, and lethargy. Several double-blind, placebo-controlled clinical trials have demonstrated that calcium supplementation (usually 1,000–1,200 mg per day) significantly reduces the severity of PMS symptoms, particularly those related to mood and affect. These effects are believed to be due to calcium's role in neurotransmitter regulation and its influence on the nervous system. For example, a landmark study published in the "American Journal of Obstetrics and Gynecology" (1998) found that women who took calcium carbonate experienced a 48% reduction in overall PMS symptoms, compared to 30% in the placebo group. Follow-up studies and meta-analyses have confirmed these results, with the greatest benefit observed in emotional and affective symptoms, such as those seen in PMS Type D.

The physiological rationale is that estrogen and progesterone fluctuations during the menstrual cycle may alter calcium homeostasis, and low calcium intake may exacerbate PMS symptoms. Supplementing with calcium appears to stabilize these fluctuations and improve neurotransmitter balance, thereby reducing depressive symptoms. Because of this consistent evidence, some clinical guidelines now recommend calcium as a first-line option for PMS symptom management, especially for mood-related symptoms. In summary, the use of calcium for PMS Type D is well-supported by scientific research and is considered both safe and effective.

More about calcium
More about PMS Type D

Products containing calcium

Nature's Sunshine Love and Peas (Sugar Free)
Nature's Sunshine AIVIA Clean Energy
Nature's Sunshine AIVIA Hydrate
Nature's Sunshine AIVIA MCT Powder
Nature's Sunshine AIVIA Plant Protein
Nature's Sunshine AIVIA Plant Protein
Nature's Sunshine AIVIA Whey Protein
Nature's Sunshine AIVIA Whey Protein
Nature's Sunshine Balanced B Complex (Vitamin B)
Nature's Sunshine Bilberry Fruit (Concentrate)
Nature's Sunshine Estro-Assured (Formerly Breast Assured)
Nature's Sunshine Calcium-Magnesium (SynerPro)
Nature's Sunshine Calcium Plus Vitamin D
Nature's Sunshine Chromium-GTF
Nature's Sunshine Coral Calcium
Nature's Sunshine Coral Calcium
Nature's Sunshine Iron (Chelated)
Nature's Sunshine Love and Peas
Nature's Sunshine Magnesium
Nature's Sunshine Mega-Chel
Nature's Sunshine MultiVitamin & Mineral (SynerPro)
Nature's Sunshine MultiVitamin & Mineral (Time Release)
Nature's Sunshine Natural Changes
Nature's Sunshine Nature's Harvest
Nature's Sunshine Power Meal
Nature's Sunshine Power Meal
Nature's Sunshine Sea Calcium (Nature's)
Nature's Sunshine Silver Shield BioGuard Hand & Body Cream
Nature's Sunshine Skeletal Strength
Nature's Sunshine Solstic Twenty-Four
Nature's Sunshine Solstic Revive
Nature's Sunshine Stixated
Nature's Sunshine Stomach Comfort (Chewable)
Nature's Sunshine Structural System (30 Day Program)
Nature's Sunshine Super Supplemental
Nature's Sunshine Super Supplemental (Without Iron)
Nature's Sunshine Super Trio
Nature's Sunshine Vitamin B6
Nature's Sunshine Vitamin C Ascorbates
Nature's Sunshine Chewable Vitamin C
Nature's Sunshine Citrus Bioflavonoids (Vitamin C)
Nature's Sunshine VitaWave
Nature's Sunshine Zinc