Evidence supporting the use of: Five-leaf Chastetree
For the health condition: PMS Type C

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Five-leaf Chastetree (Vitex negundo) is traditionally used in Ayurvedic and other Asian medicine systems for a range of gynecological conditions, including premenstrual syndrome (PMS). PMS Type C is characterized by symptoms such as cravings (especially for sweets), headaches, and fatigue, primarily attributed to fluctuations in blood sugar and estrogen levels. While the European variety Vitex agnus-castus (Chasteberry) has some scientific evidence supporting its use for PMS, Five-leaf Chastetree (Vitex negundo) is mainly supported by traditional usage rather than robust clinical research.

Historical texts and ethnobotanical literature describe Vitex negundo as a remedy for menstrual irregularities, cramps, and discomforts related to the menstrual cycle. However, there is minimal direct evidence from controlled clinical trials specifically evaluating its effectiveness for PMS Type C symptoms. The mechanisms proposed in traditional medicine include its anti-inflammatory, analgesic, and mild hormone-modulating properties. Some phytochemical studies have identified flavonoids and other compounds with potential biological activity, but these findings have not been directly linked to improvements in PMS Type C in clinical settings.

In summary, while Five-leaf Chastetree is used in traditional medicine to support menstrual health, there is limited scientific validation for its efficacy in treating PMS Type C specifically. Current use for this purpose is primarily based on historical precedent rather than modern clinical evidence.

More about Five-leaf Chastetree
More about PMS Type C

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