Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Chastetree (Vitex agnus-castus), also known as chasteberry, has been studied for its effects on premenstrual syndrome (PMS), including PMS Type C, which is characterized primarily by carbohydrate cravings and symptoms related to blood sugar fluctuations. Most scientific research on Chastetree focuses on general PMS symptoms, such as breast tenderness, irritability, mood swings, and bloating. The presumed mechanism involves modulation of prolactin and effects on the dopaminergic system, which may, in turn, help regulate mood and certain physical symptoms.

Several randomized controlled trials and meta-analyses have found that Chastetree extract can reduce the severity of general PMS symptoms, particularly mastalgia (breast pain) and mood disturbances. However, there is limited direct evidence specifically targeting PMS Type C or carbohydrate cravings. The benefit for PMS Type C is therefore extrapolated from broader PMS studies, rather than from targeted trials. The European Medicines Agency and some clinical guidelines acknowledge Chastetree's role in alleviating PMS symptoms based on moderate-quality evidence.

In summary, while Chastetree is supported by scientific evidence for alleviating general PMS symptoms, evidence for its use specifically in PMS Type C is indirect and limited. Its use for PMS Type C is plausible but not conclusively proven.

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