Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E (including its form tocopheryl succinate) has been studied as a potential treatment for peripheral neuropathy, particularly in the context of neuropathy caused by vitamin E deficiency. Scientific evidence supports the use of vitamin E supplementation for neuropathy that is secondary to conditions causing vitamin E deficiency, such as fat malabsorption syndromes, certain genetic disorders (e.g., abetalipoproteinemia), or chronic cholestatic liver disease. In these cases, vitamin E supplementation can significantly improve neurological symptoms, including neuropathy.

However, for peripheral neuropathy unrelated to vitamin E deficiency—such as diabetic neuropathy or chemotherapy-induced neuropathy—scientific evidence supporting the efficacy of vitamin E supplementation is limited and inconsistent. Some small studies have explored its use, but results have not demonstrated clear or significant benefits for these broader forms of neuropathy. Systematic reviews and guidelines generally do not recommend vitamin E as a routine treatment for peripheral neuropathy in the absence of a documented deficiency.

In summary, while there is scientific validation for vitamin E's role in treating neuropathy due to deficiency states, evidence is lacking for its effectiveness in most other forms of peripheral neuropathy. The evidence level is therefore rated as 2: supportive for deficiency-related cases, but insufficient for general use in peripheral neuropathy.

More about Vitamin E (tocopheryl succinate)
More about Peripheral Neuropathy

Other ingredients used for Peripheral Neuropathy

Other health conditions supported by Vitamin E (tocopheryl succinate)

Products containing Vitamin E (tocopheryl succinate)