Evidence supporting the use of: Gotu kola
For the health condition: Peripheral Neuropathy
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Gotu kola (Centella asiatica) has a long history of use in traditional medicine systems such as Ayurveda and Traditional Chinese Medicine, where it is employed as a tonic for nerve health and to improve circulation. The rationale for its use in peripheral neuropathy is largely based on its reported abilities to enhance microcirculation, promote wound healing, and support nerve regeneration. Traditionally, practitioners have recommended gotu kola to address symptoms like numbness, tingling, and poor peripheral blood flow, which are common in peripheral neuropathy.
From a scientific perspective, there is a modest body of preclinical research suggesting that compounds in gotu kola, such as asiaticoside and madecassoside, possess neuroprotective, antioxidant, and anti-inflammatory effects, which could theoretically benefit nerve health. Some animal studies have shown that gotu kola extracts can help improve nerve conduction velocity and reduce oxidative stress in models of nerve injury or diabetic neuropathy. However, high-quality clinical trials in humans specifically examining gotu kola for peripheral neuropathy are extremely limited. The majority of the evidence is indirect or extrapolated from studies on wound healing or general cognitive support.
In summary, gotu kola’s use for peripheral neuropathy is primarily rooted in traditional medicine, with some preliminary scientific findings providing a basis for further investigation. However, robust clinical evidence is lacking, so its use is best considered as complementary and should not replace standard medical therapies for peripheral neuropathy.
Other ingredients used for Peripheral Neuropathy
acetyl l-carnitineashwagandha
capsaicinoids
coenzyme Q10 (CoQ10)
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
ginkgo biloba
gotu kola
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
l-arginine
l-carnitine
l-glutathione
lion's mane
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
phospholipids
pine bark
quercetin
resveratrol
thiamin (vitamin B1)
tocotrienols
vitamin B
vitamin D
vitamin E
β-nicotinamide mononucleotide (NMN)
AMP-activated protein kinase (AMPK)
Agmatine
Alpha-Lipoic Acid
anthocyanosides
Arginine silicate
Benfotiamine
Dihydrolipoic Acid
Eicosapentaenoic Acid
Other health conditions supported by gotu kola
AbrasionsAnal Fistula or Fissure
Anxiety
Anxiety Disorders
Arthritis
Backache
Bruises (healing)
Burns and Scalds
Cancer (natural therapy for)
Capillary Weakness
Carbuncles
Cellulite
Circulation (poor)
Convalescence
Cuts
Depression
Dermatitis
Diabetes
Digestion (poor)
Dizziness
Eczema
Edema
Fatigue
Gangrene
Gastritis
Gingivitis
Hair (loss or thinning)
Headache (general)
Hemorrhoids
Hypertension
Inflammation
Insomnia
Memory and Brain Function
Migraine
Nervous Exhaustion
Nervousness
Neuralgia and Neuritis
Pain (general remedies for)
Parkinson's Disease
Peripheral Neuropathy
Phlebitis
Psoriasis
Rashes and Hives
Scars / Scar Tissue
Spider Veins
Stress
Stretch Marks
Wounds and Sores