Evidence supporting the use of: Ashwagandha
For the health condition: Peripheral Neuropathy
Synopsis
Source of validity: Traditional
Rating (out of 5): 1
Ashwagandha (Withania somnifera) is a prominent herb in traditional Ayurvedic medicine, where it is widely used as a "rasayana" or rejuvenator. While ashwagandha is primarily known for its adaptogenic and anti-inflammatory properties, its direct use for treating or supporting peripheral neuropathy is not strongly rooted in either traditional practice or modern clinical research. Some traditional Ayurvedic formulations for nerve health may contain ashwagandha, often combined with other herbs like Guduchi or Bala, based on its general nerve-strengthening and anti-inflammatory reputation. However, there is limited direct historical documentation specifically recommending ashwagandha for peripheral neuropathy.
On the scientific front, preclinical studies (in animals and cell cultures) have shown that ashwagandha extracts can exhibit neuroprotective effects, reduce oxidative stress, and modulate inflammatory pathways, which in theory could be beneficial for neuropathic conditions. However, there are no robust human clinical trials directly examining ashwagandha as a monotherapy for peripheral neuropathy. Thus, while its use is sometimes justified in traditional systems for general nerve health and vitality, the evidence specifically supporting its efficacy in peripheral neuropathy is weak and largely extrapolated from broader claims regarding nerve function and inflammation. More research is needed to validate its effectiveness for this specific condition.
Other ingredients used for Peripheral Neuropathy
acetyl l-carnitineashwagandha
capsaicinoids
coenzyme Q10 (CoQ10)
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
ginkgo biloba
gotu kola
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
l-arginine
l-carnitine
l-glutathione
lion's mane
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
phospholipids
pine bark
quercetin
resveratrol
thiamin (vitamin B1)
tocotrienols
vitamin B
vitamin D
vitamin E
β-nicotinamide mononucleotide (NMN)
AMP-activated protein kinase (AMPK)
Agmatine
Alpha-Lipoic Acid
anthocyanosides
Arginine silicate
Benfotiamine
Dihydrolipoic Acid
Eicosapentaenoic Acid
Other health conditions supported by ashwagandha
Addictions (drugs)Addictions (general remedies for)
Adrenal Fatigue
Afterbirth Pain
Aging (prevention)
Alcoholism
Allergies (respiratory)
Alzheimer's Disease
Amenorrhea
Anemia
Angina
Anorexia
Anxiety
Anxiety Disorders
Appetite (deficient)
Anger (excessive)
Arthritis
Asthma
Athletic and Exercise Aids
Attention Deficit Disorder
Autoimmune Disorders
Backache
Bedwetting
Body Building
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cholesterol (high)
Chronic Obstructive Pulmonary Disorder
Circulation (poor)
Concentration (poor)
Depression
Diabetes
Digestion (poor)
Emotional Sensitivity
Endurance (lack of)
Energy (lack of)
Epilepsy
Erectile Dysfunction
Exercise
Fatigue
Fear (excessive)
Fibromyalgia Syndrome
Goiter
Grief and Sadness
Hair (graying)
Hair (loss or thinning)
Hair Care (general)
Headache (general)
Headache (tension)
Heart (weakness)
Hot Flashes
Hypertension
Hypothyroid
Hysteria
Infertility
Inflammation
Insomnia
Irritability
Leucorrhea
Lyme Disease
Memory and Brain Function
Menopause
Menorrhagia
Menstrual Irregularity
Menstruation (scant)
Mental Illness
Migraine
Miscarriage (prevention)
Mood Swings
Muscle Tone (lack of)
Nervous Exhaustion
Nervousness
Neurosis
Nightmares
Nocturnal Emission
Obsessive Compulsive Disorder
Osteoporosis
Pain (general remedies for)
Parkinson's Disease
Peripheral Neuropathy
Pets (supplements for)
PMS (general)
PMS Type C
PMS Type D
Post Partum Depression
Post Partum Weakness
Post Traumatic Stress Disorder
Premature Ejaculation
Prolapsed Uterus
Rheumatoid Arthritis
Sex Drive (low)
Sleep (restless and disturbed)
Stress
Syphilis
Tension
Testosterone (low)
Thinking (cloudy)
TMJ
Tremors
Triglycerides (high)
Tuberculosis
Vitiligo
Weight Gain
Weight Loss
Worry
Wounds and Sores
Products containing ashwagandha
Nature's Sunshine 5-HTP Power
Nature's Sunshine AdaptaMax
Nature's Sunshine Joint Health (Ayurvedic)
Nature's Sunshine Glandular System
Nature's Sunshine Nervous System (30 Day Program)
Nature's Sunshine Power Meal
Nature's Sunshine Power Meal
Nature's Sunshine Ultrabiome DTX