Evidence supporting the use of: Salidrosides
For the health condition: Parkinson's Disease

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Salidroside is a primary bioactive compound found in Rhodiola rosea, a plant used traditionally in Eastern medicine. Recent scientific studies have explored its neuroprotective properties, particularly in the context of neurodegenerative diseases like Parkinson's Disease (PD). Preclinical studies in cell cultures and animal models indicate that salidroside may protect dopaminergic neurons against toxins such as MPTP and 6-OHDA, which are commonly used to simulate PD pathology. The proposed mechanisms include antioxidant effects, reduction of oxidative stress, anti-apoptotic activity, and modulation of inflammatory pathways. For example, several studies report that salidroside can reduce markers of oxidative damage and apoptosis in dopaminergic neurons, and may improve behavioral outcomes in Parkinsonian animal models (source).

However, there is currently a lack of robust human clinical trials evaluating the efficacy or safety of salidroside in Parkinson's patients. The existing evidence is limited to in vitro and animal studies, which, while promising, are insufficient to justify its routine use in clinical practice for PD. More high-quality research, especially randomized controlled trials in humans, is needed to confirm these findings and establish therapeutic protocols.

More about Salidrosides
More about Parkinson's Disease

Products containing Salidrosides

We currently have no products on Caring Sunshine that contain this ingredient.