Evidence supporting the use of: Salidrosides
For the health condition: Parkinson's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Salidroside is a primary bioactive compound found in Rhodiola rosea, a plant used traditionally in Eastern medicine. Recent scientific studies have explored its neuroprotective properties, particularly in the context of neurodegenerative diseases like Parkinson's Disease (PD). Preclinical studies in cell cultures and animal models indicate that salidroside may protect dopaminergic neurons against toxins such as MPTP and 6-OHDA, which are commonly used to simulate PD pathology. The proposed mechanisms include antioxidant effects, reduction of oxidative stress, anti-apoptotic activity, and modulation of inflammatory pathways. For example, several studies report that salidroside can reduce markers of oxidative damage and apoptosis in dopaminergic neurons, and may improve behavioral outcomes in Parkinsonian animal models (source).

However, there is currently a lack of robust human clinical trials evaluating the efficacy or safety of salidroside in Parkinson's patients. The existing evidence is limited to in vitro and animal studies, which, while promising, are insufficient to justify its routine use in clinical practice for PD. More high-quality research, especially randomized controlled trials in humans, is needed to confirm these findings and establish therapeutic protocols.

More about Salidrosides
More about Parkinson's Disease

Other ingredients used for Parkinson's Disease

Acetyl L-carnitine
Akkermansia muciniphila
algal oil
ashwagandha
beta caryophyllene
black garlic
butyrate triglyceride
catechins
citicoline
coenzyme Q10 (CoQ10)
curcumin
DHA (docosahexaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fava bean
fisetin
fish oil
ginkgo biloba
gotu kola
green tea
L-carnosine
L-glutathione
lion's mane
luteolin
medium chain triglycerides (MCT)
Melatonin
N-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
phosphatidylserine
phytocannabinoids
quercetin
resveratrol
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
specialized pro-resolving mediators (SPMs)
spirulina
sulforaphane glucosinolate
ubiquinol
Urolithin A
velvet bean
vitamin D
vitamin D3
β-nicotinamide mononucleotide (NMN)
lingzhi
ferulic acid
AMP-activated protein kinase (AMPK)
1,3,7-Trimethylpurine-2,6-dione
7,8-Dihydroxyflavone
apigenin
Agmatine
astragalin
biopterin
baicalein
brahmi
broad bean
bacoside
baicalin
catalpol
creatine
C-phycocyanin
cannabidiol
carnosic acid
decarboxylase
ergothioneine
eicosapentaenoic acid
fo-ti
Ginsenosides
Gypenoside
Glycosphingolipids
Glucoraphanin
gastrodin
Haematococcus pluvialis
Honokiol
hericium mushroom
inosine
isoliquiritigenin
icariin
Jatamansi
Kaempferol
mangiferin
Myricetin
magnolol
NADH
Nobiletin
Oleuropein
Phosphocreatine
Puerain
pyrroloquinoline quinone
Puerarin
paeoniflorin
Palmitoylethanolamide (PEA)
Salidroside
Salvianolic acid
Shilajit
Sulforaphane
Tumerone
Tanshinone
Trehalose
Triacetyluridine
Uncaria
Vitexin
Withanolides
Wogonin
Xanthine
Xanthohumol
Xanthone

Products containing Salidrosides

We currently have no products on Caring Sunshine that contain this ingredient.