Evidence supporting the use of: EGCG
For the health condition: Parkinson's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Epigallocatechin gallate (EGCG) is a polyphenol found predominantly in green tea. Its use in supporting or treating Parkinson’s Disease (PD) is based on preclinical scientific evidence rather than traditional medicine. Several in vitro and animal studies have demonstrated that EGCG exhibits neuroprotective, antioxidant, and anti-inflammatory properties, which may be beneficial in neurodegenerative diseases like PD. EGCG has been shown to reduce oxidative stress, inhibit the aggregation of alpha-synuclein (a protein implicated in PD pathology), and protect dopaminergic neurons in various animal models of PD (PMID: 31467999). Additionally, EGCG may modulate signaling pathways related to cell survival and apoptosis, further contributing to neuroprotection. However, it is important to note that while the preclinical data are promising, there is currently a lack of robust clinical trials in humans to confirm these effects. Most of the supportive evidence comes from laboratory and animal studies, with limited data on safety, optimal dosing, or efficacy in human PD patients. Therefore, EGCG cannot yet be recommended as a validated treatment for PD, but it remains an area of active research. The evidence level is rated as 2, reflecting preclinical promise but insufficient human data.

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Other ingredients used for Parkinson's Disease

Acetyl L-carnitine
Akkermansia muciniphila
algal oil
ashwagandha
beta caryophyllene
black garlic
butyrate triglyceride
catechins
citicoline
coenzyme Q10 (CoQ10)
curcumin
DHA (docosahexaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fava bean
fisetin
fish oil
ginkgo biloba
gotu kola
green tea
L-carnosine
L-glutathione
lion's mane
luteolin
medium chain triglycerides (MCT)
Melatonin
N-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
phosphatidylserine
phytocannabinoids
quercetin
resveratrol
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
specialized pro-resolving mediators (SPMs)
spirulina
sulforaphane glucosinolate
ubiquinol
Urolithin A
velvet bean
vitamin D
vitamin D3
β-nicotinamide mononucleotide (NMN)
lingzhi
ferulic acid
AMP-activated protein kinase (AMPK)
1,3,7-Trimethylpurine-2,6-dione
7,8-Dihydroxyflavone
apigenin
Agmatine
astragalin
biopterin
baicalein
brahmi
broad bean
bacoside
baicalin
catalpol
creatine
C-phycocyanin
cannabidiol
carnosic acid
decarboxylase
ergothioneine
eicosapentaenoic acid
fo-ti
Ginsenosides
Gypenoside
Glycosphingolipids
Glucoraphanin
gastrodin
Haematococcus pluvialis
Honokiol
hericium mushroom
inosine
isoliquiritigenin
icariin
Jatamansi
Kaempferol
mangiferin
Myricetin
magnolol
NADH
Nobiletin
Oleuropein
Phosphocreatine
Puerain
pyrroloquinoline quinone
Puerarin
paeoniflorin
Palmitoylethanolamide (PEA)
Salidroside
Salvianolic acid
Shilajit
Sulforaphane
Tumerone
Tanshinone
Trehalose
Triacetyluridine
Uncaria
Vitexin
Withanolides
Wogonin
Xanthine
Xanthohumol
Xanthone

Products containing EGCG

We currently have no products on Caring Sunshine that contain this ingredient.