Evidence supporting the use of: Calcium acetate
For the body system: Parathyroid Glands
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Calcium acetate is primarily used in clinical medicine to control hyperphosphatemia (high blood phosphate levels) in patients with chronic kidney disease (CKD), particularly those on dialysis. Its mechanism involves binding dietary phosphate in the gastrointestinal tract, thereby reducing phosphate absorption. The relevance to the parathyroid glands lies in the regulation of calcium and phosphate balance in the body—a crucial aspect of parathyroid function. In CKD, phosphate retention stimulates parathyroid hormone (PTH) secretion, leading to secondary hyperparathyroidism. By lowering serum phosphate levels, calcium acetate indirectly helps to reduce PTH secretion, thereby supporting the health of the parathyroid system and mitigating complications such as renal osteodystrophy. Multiple randomized controlled trials and meta-analyses have confirmed the efficacy of calcium acetate in lowering serum phosphate and reducing PTH levels in CKD patients. Guidelines from nephrology societies (e.g., KDIGO, KDOQI) recommend the use of phosphate binders, including calcium acetate, for managing mineral and bone disorders in CKD. However, its use is specific to patients with kidney dysfunction and not for general support of parathyroid gland health in the broader population. There is limited evidence for its use outside this context. In summary, calcium acetate has a well-established, scientifically validated role in supporting the parathyroid gland system, specifically in the management of secondary hyperparathyroidism in CKD.
Other ingredients that support Parathyroid Glands
calciumkelp
magnesium
vitamin D
vitamin D3
zinc
trace minerals
bladderwrack
Other body systems supported by Calcium acetate
BloodKidneys
Parathyroid Glands
Skeletal System (Bones)