Evidence supporting the use of: L-taurine
For the body system: Parasympathetic Nervous System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

L-taurine, a sulfur-containing amino acid, has some scientific backing for its influence on the parasympathetic nervous system (PNS), though the evidence is moderate rather than conclusive. Taurine is well-known for its role in neuromodulation, osmoregulation, and membrane stabilization within the central nervous system. Several animal studies have demonstrated that taurine may enhance parasympathetic (vagal) activity and reduce sympathetic outflow, leading to decreased heart rate and blood pressure. For example, research in rodents suggests that taurine supplementation can increase vagal tone and promote relaxation responses, which are mediated by the PNS. Human data are less abundant, but some small clinical studies indicate taurine may have beneficial effects on cardiovascular parameters—such as blood pressure—partially through modulation of autonomic balance in favor of the parasympathetic system. Additionally, taurine has demonstrated anxiolytic (anxiety-reducing) effects in preclinical models, possibly due to its interaction with neurotransmitter systems that support parasympathetic activity. However, while these findings are promising, large-scale randomized controlled trials in humans directly linking taurine supplementation to enhanced parasympathetic function are lacking. The current evidence supports a plausible mechanism and some physiological effects, but further research is needed for definitive conclusions. Therefore, the scientific evidence for taurine's support of the parasympathetic nervous system is present but moderate in strength.

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