Evidence supporting the use of: American Wormseed
For the health condition: Parasites (tapeworm)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
American Wormseed (Chenopodium ambrosioides), also known as epazote, has a long history of traditional use as an anthelmintic (a substance that expels parasitic worms) in both indigenous and folk medicine, particularly in the Americas. Historically, its seeds and oil were commonly used to treat intestinal parasites, including tapeworms, roundworms, and hookworms. The plant contains compounds such as ascaridole, which are believed to be responsible for its anti-parasitic effects. In the late 19th and early 20th centuries, oil of chenopodium was even listed in the United States Pharmacopoeia as a treatment for intestinal worms. However, while there is some pharmacological evidence showing toxicity of chenopodium oil to parasites, scientific validation through modern clinical trials is limited, and concerns about the toxicity of ascaridole and other constituents have led to a decline in its medicinal use. The use of American Wormseed is now largely considered historical or traditional, and safer, more effective anthelmintics are now preferred in modern medicine. Despite its traditional use, scientific evidence supporting its efficacy and safety remains insufficient by current standards.
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