Evidence supporting the use of: Ipomoea jalapa
For the health condition: Parasites (nematodes, worms)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ipomoea jalapa, commonly known as jalap, has a long history of use as a traditional remedy for intestinal parasites, particularly nematodes and other worms. The dried tuberous root of this plant has been utilized since the 16th century in Central and South America as a powerful purgative, with European adoption in the following centuries. Its use as an anthelmintic is primarily due to its strong cathartic (laxative) properties, which were believed to expel intestinal parasites by increasing intestinal motility and fluid secretion.

Historical texts and pharmacopeias from the 17th to 19th centuries document jalap's application for worm infestations, often as a component in compounded remedies. The primary active constituents, resin glycosides (notably jalapin), are responsible for the root's drastic purgative effects. However, there is little modern scientific research directly validating its efficacy or safety as an anthelmintic by current standards; its role is largely inferred from its ability to induce diarrhea rather than any specific antiparasitic activity. Furthermore, the harshness of its cathartic action has led to decreased use in contemporary medicine, replaced by more targeted and less toxic anthelmintic drugs.

In summary, the use of Ipomoea jalapa against intestinal parasites is justified by historical and traditional practice, but lacks robust scientific validation or clinical evidence by modern standards.

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