Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Achyranthes, particularly Achyranthes aspera, has been used in traditional medicine systems such as Ayurveda, Unani, and folk medicine for a variety of purposes, including as a remedy for intestinal parasites. Historical texts and ethnobotanical surveys document the use of Achyranthes aspera seeds, roots, and leaves for expelling worms and treating other parasitic infections. The plant is believed to act as a vermifuge, aiding in the removal of intestinal parasites. However, the majority of this evidence comes from traditional knowledge and practices rather than rigorous scientific validation.

A limited number of preclinical studies have explored the anti-parasitic or anthelmintic properties of Achyranthes extracts, with some in vitro and animal research indicating mild activity against certain helminths. For example, methanolic and aqueous extracts of the plant have shown some efficacy against earthworm models (Pheretima posthuma) in laboratory settings. Nevertheless, these studies are preliminary, and there is insufficient clinical data to confirm efficacy in humans. Overall, the use of Achyranthes for parasites is primarily justified by traditional use, with only modest preclinical support and a lack of robust scientific or clinical trials.

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