Evidence supporting the use of: Acetyl l-carnitine
For the health condition: Paralysis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Acetyl L-carnitine (ALC) has been studied for its potential neuroprotective and neuroregenerative properties, particularly in conditions involving nerve damage or degeneration. Its use in the context of paralysis is primarily related to its potential benefits in peripheral neuropathies and nerve injury rather than central causes of paralysis (such as spinal cord injury or stroke). Several small clinical trials and animal studies have explored ALC's effects on nerve regeneration, reduction of neuropathic pain, and improvement of nerve conduction. For example, some studies have shown that ALC supplementation can improve sensory and motor nerve function in patients with diabetic neuropathy and other peripheral neuropathies, suggesting a possible role in supporting nerve recovery. However, the direct evidence for ALC in the treatment or significant functional recovery of paralysis per se—especially paralysis caused by central nervous system injury—is limited. Most of the clinical research focuses on neuropathic pain or mild to moderate nerve dysfunction rather than complete paralysis. There is some preclinical evidence suggesting that ALC might help promote neuronal repair and reduce oxidative stress after nerve injury, but robust, large-scale clinical trials in humans with paralysis are lacking. As a result, while there is scientific rationale and some preliminary evidence, the overall strength of the evidence specifically for treating or supporting paralysis is weak to moderate, justifying a rating of 2 out of 5.

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Products containing acetyl l-carnitine

Nature's Sunshine Solstic Cardio