Evidence supporting the use of: Ashwagandha
For the health condition: Pain (general remedies for)

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ashwagandha (Withania somnifera) has a long history of use in traditional Ayurvedic medicine as a general remedy for pain, particularly for conditions involving chronic pain, inflammation, and rheumatism. Ayurvedic practitioners have utilized ashwagandha root extracts for centuries to alleviate discomfort associated with arthritis, muscle pain, and even nerve-related pain. Traditional texts often describe ashwagandha as a “rasayana” (rejuvenator) and “balya” (strength-promoting) herb, believed to restore balance and reduce pain through its adaptogenic and anti-inflammatory properties.

Scientific evidence supporting ashwagandha’s analgesic (pain-relieving) effects is growing but remains limited and mostly preliminary. Animal studies have demonstrated that ashwagandha root extracts may reduce pain and inflammation, possibly through modulation of inflammatory pathways and inhibition of pro-inflammatory cytokines. Some small human studies suggest potential benefits for pain reduction, particularly in osteoarthritis and rheumatoid arthritis, but these studies often have methodological limitations such as small sample sizes and lack of rigorous controls. Overall, while traditional use is well documented and biological plausibility exists, robust clinical trials confirming its efficacy for general pain management in humans are still lacking.

In summary, ashwagandha’s use for pain is primarily justified by traditional practices, with emerging but not definitive scientific support. Individuals interested in using ashwagandha for pain should consult a healthcare professional, particularly if taking other medications or managing chronic conditions.

More about ashwagandha
More about Pain (general remedies for)

Other ingredients used for Pain (general remedies for)

allspice
alpha-pinene
arjun tree
ashwagandha
waterhyssop
bamboo
barberry
myrobalan
benegut perilla (proprietary)
beta caryophyllene
beta-pinene
betel
bisabolol
black pepper
radish
Indian frankincense
bromelain
bupleurum falcatum
burdock
cabbage leaf
California poppy
camu camu
cassia bark
celery
chen pi
cherry
Chinese salvia root
chymotrypsin
cissus quadrangularis
collagen
cordyceps
turmeric
curcumin
devil's claw
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
dog rose
ethanol
fennel
fenugreek
flaxseed
fruit blend (proprietary)
gelatin
ginger
gooseberry
gotu kola
honeysuckle
Japanese sophora
jujube
kudzu
l-phenylalanine
lovage
magnesium
methylsulfonylmethane (MSM)
mint
nettle
spruce
okra
orange
peppermint oil
perilla
polygala root
protease
pumpkin
quail egg
reishi mushroom
rose oil
rutin
saffron
sage
black ginger
specialized pro-resolving mediators (SPMs)
strawberry
vitamin D
watercress
mulberry
white willow
zhejiang fritillary
sarsaparilla
yellow root
boneset
catnip
typhonium
hyssop
cardamom
atractylodes
alpinia galangal
clerodendrum indicum
hedychium spicatum
inula racemosa
anise
pistacia integerrima gall
paederia foetida
smilax
fumaria parviflora
rubia cordifolia
swertia
chaff flower
lingusticum wallichii
goldenrod
yarrow
prickly ash
morus
root tuber
silk tree
haliotis
juniper berries
solomon's seal
amber
flowering quince
cistanche
dioscorea
teasel
sweetgums
lotus seed
birch
queen of the meadow
anemarrhena asphodeloides
purslane
yucca
barrenwort
wintergreen
camphor oil
aster root
gentiana macrophylla
shepherd's purse
yerba mate
fungal enzymes blend (proprietary)
peach
noni
wood betony
biota seed
white oak
abies spectabilis
Sichuan pepper
soursop
geranium
arnica
clematis
sea salt
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Alcohol
Aralia
Arjuna
akebia
Antler
Agastache
Alseodaphne andersonii
Angel's Trumpet
Aquilegia viridiflora
Alpha-Humulene
Alpha-terpineol
Agrimony
Antrodia camphorata
Achyranthes
Auricularia
Abrus
Alchornea
American Pawpaw
Amomum
Asarum heterotropoides
Albizia
Alchemilla
Aconite
Asafoetida
Ajuga
Aucubin
Andrographolide
Anserina
Agmatine
Aerva lanata
Agarwood
American Liverleaf
Anemone
Aquilegia formosa
Asam gelugor
Angostura
Andrographis
Alsonia scholaris
Actaea spicata
Agonandra
Agrimonia pilosa
Acetylsalicylic acid
Acer Truncatum bunge
Arjunic Acid
allyl isothiocyanate
Aspen
Ashoka
Argan nut oil
Asarabacca
Abuta
Alstonia macrophylla
Amor seco
Arani
Arisaema
Atractylone
Betony
Baikal Skullcap
Blue Flag
Bryonia
Baliospermum
Black spruce
Blackthorn
Bleeding Heart
Bulnesia sarmientoi
bergenin
Blubber oil
Breadnut
Blepharis
Boswellic Acid
Bistort
Baccharis dracunculifolia
Barleria
Berberis (unspecified)
Bougainvillea
Brazillian peppertree
Bugbane
Bisabolene
Benfotiamine
Bael
Butternut
Bogbean
Black Gram
Bauhinia
Boswellia
Bethroot
Banyan
Black willow
Ba Ji Tian
Barbasco
Barbary matrimony vine
Borassus aethiopum
Borage
Black root
Baobab
Bupleurum
Bittersweet
Bassia scoparia
Burning Bush
Black Hellebore
Bee venom
Bergenia
Bottle gourd
Cumin
Centella triterpenes
Calendula
Casearia esculenta
Common Monkey Flower
Chinese Mountain Ant
California Redbud
Calotropis gigantea
Carrapicho
Cucurbita
Codonopsis
Cnidium
Clerodendrum phlomidis
Cactus
Cynomorium
Cinquefoil
Cyathula
Citron
Cashew
Chinese Fleeceflower
Cymbidium goeringii
Cannabinol
Cramp Bark
Chinese Pond Turtle
Cajuput
Chuchuhuasi
Cymbopogon Martini
Centella asiatica
Coca
Capers
Celandine
Cinnamic Acid
Ceylon Leadwort
Cetylated Fatty Acids
Cissus sicyoides
Chinese Ligustrum berry
Campylandra fimbriata
Chenopodium
Chilean Wildnut
Cistus
Corktree
Cubeb
cypress
Cowslip
Cranesbill
Crinum latifolium
Chaenomeles lagenaria
Cannabidiol
Carlina
Calamus
Cherimoya
Cyanthillium cinereum
Corydalis
Cynodon dactylon
Chiococca alba
Collinsonia
Celastrus
Copaiba Oil
Colocynth
cola nut
Cynanchum
California False Hellebore
Cupuacu
Casearia sylvestris
Culvers Root
Currant
Calycophyllum
Cannabidiolic acid
Dimorphandra mollis
D-phenylalanine
Didymocarpus
Dendrobine
DIVI-DIVI
Dicentra formosa
Danshen
Dense Fruit Dittany
Deer Root
Dodeca-2E, 4E-Dienoic Acid Isobutylamide
Dill
Dianthrone
Dwarf Morning Glory
Dolichos
Dimethyl sulfoxide (DMSO)
Dimorphandra gardneriana
Dipsacus
Dodeca-2E, 4E, 8Z, 10Z/Etetraenoic Acid Isobutylamide
European Elder
Elk antler
Emblicanin
Emu Oil
Echinodorus
Eupatorium
Elemi
Embelia
Fig
Goldthread
Lotus
Lily
Mistletoe
Mimosa
Orchid
Poppy
Rose
Spikenard
Snakeroot (unspecified)
Sweet Orange alcohol
Vervain
walnut

Other health conditions supported by ashwagandha

Addictions (drugs)
Addictions (general remedies for)
Adrenal Fatigue
Afterbirth Pain
Aging (prevention)
Alcoholism
Allergies (respiratory)
Alzheimer's Disease
Amenorrhea
Anemia
Angina
Anorexia
Anxiety
Anxiety Disorders
Appetite (deficient)
Anger (excessive)
Arthritis
Asthma
Athletic and Exercise Aids
Attention Deficit Disorder
Autoimmune Disorders
Backache
Bedwetting
Body Building
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cholesterol (high)
Chronic Obstructive Pulmonary Disorder
Circulation (poor)
Concentration (poor)
Depression
Diabetes
Digestion (poor)
Emotional Sensitivity
Endurance (lack of)
Energy (lack of)
Epilepsy
Erectile Dysfunction
Exercise
Fatigue
Fear (excessive)
Fibromyalgia Syndrome
Goiter
Grief and Sadness
Hair (graying)
Hair (loss or thinning)
Hair Care (general)
Headache (general)
Headache (tension)
Heart (weakness)
Hot Flashes
Hypertension
Hypothyroid
Hysteria
Infertility
Inflammation
Insomnia
Irritability
Leucorrhea
Lyme Disease
Memory and Brain Function
Menopause
Menorrhagia
Menstrual Irregularity
Menstruation (scant)
Mental Illness
Migraine
Miscarriage (prevention)
Mood Swings
Muscle Tone (lack of)
Nervous Exhaustion
Nervousness
Neurosis
Nightmares
Nocturnal Emission
Obsessive Compulsive Disorder
Osteoporosis
Pain (general remedies for)
Parkinson's Disease
Peripheral Neuropathy
Pets (supplements for)
PMS (general)
PMS Type C
PMS Type D
Post Partum Depression
Post Partum Weakness
Post Traumatic Stress Disorder
Premature Ejaculation
Prolapsed Uterus
Rheumatoid Arthritis
Sex Drive (low)
Sleep (restless and disturbed)
Stress
Syphilis
Tension
Testosterone (low)
Thinking (cloudy)
TMJ
Tremors
Triglycerides (high)
Tuberculosis
Vitiligo
Weight Gain
Weight Loss
Worry
Wounds and Sores