Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Dissolved oxygen is scientifically validated for the treatment and support of oxygen deficiency (hypoxemia or hypoxia). Oxygen therapy, which involves the medical administration of oxygen gas (O₂)—sometimes dissolved in fluids for certain clinical situations—is a mainstay of modern medicine. The primary rationale is that oxygen is essential for cellular respiration and energy production. In cases of oxygen deficiency, such as respiratory failure, carbon monoxide poisoning, or severe anemia, supplemental oxygen increases the partial pressure of oxygen in the blood, thereby enhancing oxygen delivery to tissues. Clinical guidelines worldwide, including those from the World Health Organization (WHO) and the American Thoracic Society, recommend oxygen supplementation as a first-line therapy for hypoxemia. The evidence base includes numerous clinical trials and decades of medical practice demonstrating that oxygen administration rapidly reverses tissue hypoxia, reduces morbidity, and can be life-saving. Delivery methods include nasal cannula, face masks, and in critical care, mechanical ventilation—each delivering oxygen dissolved in inspired air to increase arterial oxygenation. While oxygen is not typically delivered as "dissolved oxygen" in beverages or supplements, the clinical use of oxygen gas or oxygen-enriched fluids is foundational in treating oxygen deficiency. Overall, the justification for using oxygen (including dissolved oxygen in medical contexts) to treat oxygen deficiency is robust and evidence-based.

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