Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Sodium citrate is scientifically validated for use in treating or supporting overacidity, particularly in conditions such as metabolic acidosis and certain types of urinary tract disorders. Sodium citrate acts as an alkalinizing agent: after ingestion, it is metabolized to bicarbonate, which helps to neutralize excess acid in the blood and urine. This mechanism is well-documented in medical literature and clinical guidelines.

In the context of overacidity (which can refer to systemic metabolic acidosis or acidic urine), sodium citrate is commonly used to increase the pH of bodily fluids. For example, it is frequently prescribed to patients with renal tubular acidosis, chronic kidney disease, or uric acid kidney stones to help correct acid-base imbalances. Its use is also recognized for symptom relief in mild dyspepsia or heartburn, as it neutralizes gastric acid, though this is less common compared to agents like sodium bicarbonate or antacids specifically formulated for gastric use.

Clinical trials and pharmacological reviews confirm the efficacy and safety of sodium citrate in these roles. It is included on the World Health Organization’s List of Essential Medicines for treating acidosis, underscoring its acceptance and validation in mainstream medicine. However, it should be used under medical supervision, as excessive administration can lead to metabolic alkalosis or sodium overload, especially in individuals with compromised kidney function.

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