Evidence supporting the use of: Potassium Citrate
For the health condition: Overacidity

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Potassium citrate is scientifically validated for use in treating certain types of "overacidity," primarily in the context of metabolic acidosis and the prevention of kidney stones. Potassium citrate is an alkalinizing agent, meaning it raises urine pH by neutralizing excess acid in the body. This property is well-documented in clinical medicine, especially for patients with renal tubular acidosis, chronic kidney disease, or those prone to uric acid or calcium oxalate kidney stones. Randomized controlled trials and clinical guidelines support its use in these conditions, demonstrating that potassium citrate can effectively correct metabolic acidosis and reduce stone formation by alkalinizing the urine and increasing urinary citrate, which inhibits stone formation.

However, potassium citrate is not typically used for gastric overacidity (such as heartburn or gastroesophageal reflux), as its action is systemic rather than localized to the stomach. Antacids like calcium carbonate or magnesium hydroxide are preferred for those conditions because they neutralize gastric acid directly. In summary, potassium citrate has robust scientific support for treating systemic overacidity and kidney stone prevention, but not for straightforward gastrointestinal acid excess.

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