Evidence supporting the use of: Glycosaminoglycans
For the body system: Other Body Parts
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Glycosaminoglycans (GAGs), such as chondroitin sulfate and hyaluronic acid, are key components of connective tissues throughout the body, including cartilage, skin, eyes, and synovial fluid. Their use to support "Other Body Parts" systems—meaning tissues beyond joints, such as skin and eyes—has scientific backing. For example, hyaluronic acid is widely used in dermatology for skin hydration and wound healing, supported by both topical and injectable studies showing improved skin elasticity and repair. Additionally, oral and injectable GAGs are used in ophthalmology to maintain eye moisture and health, and there is evidence supporting their use in the management of dry eyes and as a surgical adjunct. Chondroitin sulfate has demonstrated some benefits in maintaining healthy cartilage and connective tissues beyond the joints. However, the strength of evidence varies by application: skin and ophthalmic uses have moderate to strong clinical research, while claims for benefits in other tissues are less robust. Overall, glycosaminoglycans have a well-established physiological role in various body parts, and their supplementation is scientifically validated for supporting multiple components of the body’s connective tissue systems.
Other body systems supported by Glycosaminoglycans
BladderGastrointestinal Tract
Joints
Mucus Membranes
Other Body Parts
Skeletal System (Bones)
Skin
Spinal Disks
Structural System
Urinary System
