Evidence supporting the use of: Silicon
For the health condition: Osteoporosis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Silicon has garnered scientific interest as a trace element potentially beneficial for bone health, with several studies exploring its role in the prevention and management of osteoporosis. Silicon is thought to be involved in bone formation and the synthesis of collagen, a key protein in bone matrix. Some observational studies have found associations between higher dietary silicon intake and increased bone mineral density (BMD), particularly in premenopausal women. Experimental animal studies also suggest that silicon supplementation can improve bone quality and accelerate bone healing. Proposed mechanisms include the stimulation of osteoblast (bone-forming cell) activity and enhancement of the deposition of calcium and other minerals in bone tissue.

Despite these promising findings, the overall body of evidence remains limited and somewhat inconclusive. Randomized controlled trials in humans are scarce, and the existing ones are generally small, short-term, or focused on surrogate outcomes rather than fracture risk or long-term bone health. As a result, silicon is not recognized as an essential nutrient for bone health in most clinical guidelines, and its supplementation is not routinely recommended for the treatment or prevention of osteoporosis.

In summary, while there is a scientific rationale and preliminary evidence suggesting a potential benefit of silicon for bone health, the strength of this evidence is currently modest (rated 2 out of 5), and more robust clinical trials are needed before silicon supplementation can be confidently recommended for osteoporosis.

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Other ingredients used for Osteoporosis

7-hydroxymatairesinol (HMR)
Alfalfa
algal oil
alpha-ketoglutarate (AKG)
anthocyanins
ashwagandha
astragalus
beta caryophyllene
sesame
blueberry
boron
bovine
broccoli
calcium
catechins
caterpillar mushroom
Cissus quadrangularis
collagen
collard
conjugated linoleic acid (CLA)
curcumin
DHEA (dehydroepiandrosterone)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
fish protein
genistein
genistin
glycitin
gooseberry
hesperetin
hesperidin
horsetail
ipriflavone
knotweed
kale
Lentinula edodes mycelia
lignans
maca
magnesium
manganese
Microcrystalline hydroxyapatite concentrate (MCHC)
olive
omega-3 fatty acids
phosphorus
pomegranate
prune
quercetin
rehmannia glutinosa
resveratrol
rutin
silicon
soybean
specialized pro-resolving mediators (SPMs)
strontium
tocotrienols
vitamin C
vitamin D
vitamin D3
vitamin K
seaweed
Whey protein
Zinc
red clover
haliotis
cistanche
dioscorea
fern
royal jelly
equol (proprietary)
barrenwort
goji berry
AMP-activated protein kinase (AMPK)
soy isoflavones
8-Prenylnaringenin
animal Tissue
antler
apigenin
Algas calcareas
Acacetin
astragaloside
ampelopsin
Algal protein
Algalin
Abalone
arctiin
astragalin
animal protein
bok choy
bovine protein
biochanin
bone protein
calycosin
cod liver oil
cyanidin
Chinese Ligustrum berry
DHEA
daidzein
diosgenin
Drynaria
diosmetin
epicatechin
ecdysteroids
eicosapentaenoic acid
Eucommia ulmoides
estrogen
fo-ti
formononetin
fish
flavanones
flavans
flavanols
flavones
Hyperoside
isoflavones
icariin
Kaempferol
Lycium
Lithothamnion
Legume protein
Mineral blend
Marine protein
Milk Protein
Naringenin
Neoeriocitrin
Puerarin
Phytoecdysteroid
Phaeophyceae
polysaccharides
procyanidin
proanthocyanidins
polyunsaturated fat
paeoniflorin
Phytoestrogens
polymethoxylated flavones
Rehmannia
Soy
Soy Protein
silica
Shilajit
Stilbenoid
Ursolic Acid
Vegetable Protein
Wakame
Xanthophyll

Products containing silicon