Evidence supporting the use of: Silica
For the health condition: Osteoporosis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Silica (silicon dioxide) has been investigated for its potential role in bone health, including the prevention and management of osteoporosis. Scientific interest arises from the observation that silicon is present in bone tissue and may play a role in bone formation and mineralization processes. Several animal studies and limited human observational studies have suggested that dietary silicon intake is positively associated with bone mineral density (BMD), particularly in premenopausal women. Some mechanisms proposed include silica’s involvement in collagen synthesis and the stimulation of osteoblast (bone-forming cell) activity.

However, direct evidence supporting the use of supplemental silica for the treatment or prevention of osteoporosis in humans is limited. Most clinical studies are observational, with few randomized controlled trials. The available interventional studies are small in sample size and sometimes use forms of silicon different from over-the-counter silica supplements. As a result, reputable organizations, including the National Osteoporosis Foundation, do not currently recommend silica supplementation as a primary or adjunct therapy for osteoporosis.

In summary, while there is a scientific rationale for investigating silica’s effects on bone health, robust clinical evidence is lacking. The current evidence base is insufficient to strongly support the use of silica supplements for osteoporosis, and its efficacy remains unproven in large, well-designed human trials.

More about silica
More about Osteoporosis

Other ingredients used for Osteoporosis

7-hydroxymatairesinol (HMR)
8-Prenylnaringenin
Abalone
Acacetin
Alfalfa
algal oil
Algal protein
Algalin
Algas calcareas
alpha-ketoglutarate (AKG)
AMP-activated protein kinase (AMPK)
ampelopsin
animal protein
animal Tissue
anthocyanins
antler
apigenin
arctiin
ashwagandha
astragalin
astragaloside
astragalus
barrenwort
beta caryophyllene
biochanin
blueberry
bok choy
bone protein
boron
bovine
bovine protein
broccoli
calcium
calycosin
catechins
caterpillar mushroom
Chinese Ligustrum berry
Cissus quadrangularis
cistanche
cod liver oil
collagen
collard
conjugated linoleic acid (CLA)
curcumin
cyanidin
daidzein
DHEA
DHEA (dehydroepiandrosterone)
dioscorea
diosgenin
diosmetin
DPA (docosapentaenoic acid)
Drynaria
ecdysteroids
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
epicatechin
equol (proprietary)
estrogen
Eucommia ulmoides
fern
fish
fish protein
flavanols
flavanones
flavans
flavones
fo-ti
formononetin
genistein
genistin
glycitin
goji berry
gooseberry
haliotis
hesperetin
hesperidin
horsetail
Hyperoside
icariin
ipriflavone
isoflavones
Kaempferol
kale
knotweed
Legume protein
Lentinula edodes mycelia
lignans
Lithothamnion
Lycium
maca
magnesium
manganese
Marine protein
Microcrystalline hydroxyapatite concentrate (MCHC)
Milk Protein
Mineral blend
Naringenin
Neoeriocitrin
olive
omega-3 fatty acids
paeoniflorin
Phaeophyceae
phosphorus
Phytoecdysteroid
Phytoestrogens
polymethoxylated flavones
polysaccharides
polyunsaturated fat
pomegranate
proanthocyanidins
procyanidin
prune
Puerarin
quercetin
red clover
Rehmannia
rehmannia glutinosa
resveratrol
royal jelly
rutin
seaweed
sesame
Shilajit
silica
silicon
Soy
soy isoflavones
Soy Protein
soybean
specialized pro-resolving mediators (SPMs)
Stilbenoid
strontium
tocotrienols
Ursolic Acid
Vegetable Protein
vitamin C
vitamin D
vitamin D3
vitamin K
Wakame
Whey protein
Xanthophyll
Zinc