Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lithothamnion is a genus of red algae that is rich in bioavailable calcium, magnesium, and trace minerals. Its powdered form is commonly used as a mineral supplement, including in the context of bone health and osteoporosis. The scientific rationale behind its use is that adequate calcium and magnesium intake supports bone mineral density, which is crucial in the management and prevention of osteoporosis. A limited number of in vitro and animal studies suggest that Lithothamnion-derived minerals may be as bioavailable as standard calcium supplements and could favorably affect bone structure and strength. For example, a pilot human study published in "Phytotherapy Research" (2011) indicated that Lithothamnion supplementation was safe and potentially beneficial for bone turnover markers in postmenopausal women, but the study was small and not definitive.

However, robust clinical trials in humans evaluating its efficacy in reducing fracture risk or substantially improving bone mineral density are lacking. Most evidence comes from basic research, small studies, or is extrapolated from knowledge about calcium supplementation in general. Therefore, while there is some scientific basis for its use, the overall level of evidence is limited, and it should not be considered a primary or sole therapy for osteoporosis without further research. Large, well-designed clinical trials are needed to firmly establish its efficacy.

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