Evidence supporting the use of: Dioscorea
For the health condition: Osteoporosis
Synopsis
Source of validity: Traditional
Rating (out of 5): 1
Dioscorea, commonly known as wild yam, has been traditionally used in various cultures, particularly in East Asian and Native American herbal medicine, for a variety of women's health concerns, including menopausal symptoms and bone health. Its use in supporting or treating osteoporosis is primarily rooted in traditional practices, rather than robust scientific validation. This traditional application is largely based on the presence of diosgenin, a plant steroid found in Dioscorea species, which can be chemically converted in laboratories into steroidal hormones, such as progesterone and estrogen. Some practitioners have hypothesized that diosgenin may exert mild estrogen-like effects in the body, potentially benefiting bone density and reducing osteoporosis risk, especially in postmenopausal women.
However, there is limited direct scientific evidence to support the efficacy of Dioscorea or diosgenin in the prevention or treatment of osteoporosis in humans. Most studies are either in vitro, animal-based, or focus on the potential mechanisms rather than clinical outcomes. Human clinical trials are sparse, and those that exist often suffer from methodological limitations. Regulatory agencies and major osteoporosis guidelines do not recognize Dioscorea as an evidence-based intervention for bone health. As a result, while Dioscorea continues to be used in some traditional and alternative medicine systems for osteoporosis, its use is not strongly supported by scientific research, and its effectiveness remains unproven in clinical settings.
Other ingredients used for Osteoporosis
7-hydroxymatairesinol (HMR)alfalfa
algal oil
alpha-ketoglutarate (AKG)
anthocyanins
ashwagandha
astragalus
beta caryophyllene
sesame
blueberry
boron
bovine
broccoli
calcium
catechins
caterpillar mushroom
cissus quadrangularis
collagen
collard
conjugated linoleic acid (CLA)
curcumin
DHEA (dehydroepiandrosterone)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
fish protein
genistein
genistin
glycitin
gooseberry
hesperetin
hesperidin
horsetail
ipriflavone
knotweed
kale
lentinula edodes mycelia
lignans
maca
magnesium
manganese
microcrystalline hydroxyapatite concentrate (MCHC)
olive
omega-3 fatty acids
phosphorus
pomegranate
prune
quercetin
rehmannia glutinosa
resveratrol
rutin
sardines
silicon
soybean
specialized pro-resolving mediators (SPMs)
strontium
tocotrienols
tomato
vitamin C
vitamin D
vitamin D3
vitamin K
seaweed
whey protein
zinc
red clover
haliotis
cistanche
dioscorea
fern
royal jelly
Equol (proprietary)
barrenwort
goji berry
AMP-activated protein kinase (AMPK)
soy isoflavones
8-Prenylnaringenin
Animal Tissue
Antler
Apigenin
Algas calcareas
Acacetin
Astragaloside
Ampelopsin
Algal protein
Algalin
Abalone
Arctiin
Astragalin
Animal protein
Bok Choy
Bovine Protein
biochanin
Bone Protein
Calycosin
Cod Liver Oil
Cyanidin
Chinese Ligustrum berry
DHEA
Daidzein
Diosgenin
Drynaria
Diosmetin
epicatechin
Ecdysteroids
Eicosapentaenoic Acid
Eucommia ulmoides
Estrogen
Isoflavones
Milk Protein
Soy Protein
Other health conditions supported by dioscorea
Abdominal PainAmenorrhea
Appetite (deficient)
Arthritis
Asthma
Backache
Breast Lumps
Breasts (enhance size)
Bronchitis
Burns and Scalds
Cancer (natural therapy for)
Cancer Treatment (reducing side effects)
Cholesterol (high)
Circulation (poor)
Constipation (adults)
Constipation (children)
Diabetes
Digestion (poor)
Dysmenorrhea
Dyspepsia
Edema
Fatigue
Fibroids (uterine)
Gastritis
Gout
Hair (loss or thinning)
Hypertension
Indigestion
Inflammation
Kidney Stones
Menopause
Menstrual Irregularity
Nausea and Vomiting
Osteoporosis
Pain (general remedies for)