Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Collagen supplementation for osteoporosis has a basis in emerging scientific evidence, though the strength of this evidence is moderate and still developing. Collagen is the most abundant protein in the bone matrix and provides a scaffold for mineralization, contributing to bone strength and structure. As people age, natural collagen production decreases, which is thought to contribute to bone fragility and increased risk of osteoporosis. Recent randomized controlled trials (RCTs) and preclinical studies suggest that oral collagen peptides may have a beneficial effect on bone metabolism. For example, several studies have shown that collagen supplementation can increase bone mineral density (BMD) and improve markers of bone formation, particularly in postmenopausal women who are at higher risk for osteoporosis. Mechanistically, collagen peptides may stimulate osteoblast activity (bone-building cells) and enhance the synthesis of bone matrix proteins. However, while these findings are promising, the quality and size of clinical trials remain limited. Most studies are small, of short duration, or sponsored by manufacturers of collagen products, raising potential bias concerns. Major osteoporosis guidelines do not yet recommend collagen as a first-line therapy, instead prioritizing established treatments like bisphosphonates, calcium, and vitamin D. Nevertheless, collagen may be considered as an adjunctive supplement for bone health, especially in populations at risk for osteoporosis, pending further high-quality research.

More about collagen
More about Osteoporosis

Other ingredients used for Osteoporosis

Other health conditions supported by collagen

Products containing collagen

Nature's Sunshine Collagen
Nature's Sunshine Collatrim
Nature's Sunshine Marine Collagen
Nature's Sunshine Marine Glo Collagen