Evidence supporting the use of: Cod liver oil
For the health condition: Osteoporosis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Cod liver oil has been traditionally used as a supplement for bone health, but there is also scientific rationale for its use in supporting or potentially treating osteoporosis. Cod liver oil is rich in vitamin D and vitamin A, both of which play important roles in bone metabolism. Vitamin D is essential for calcium absorption in the gut and maintaining adequate serum calcium and phosphate levels, which are necessary for normal bone mineralization. Several observational studies and clinical trials have shown that vitamin D supplementation can reduce bone loss and lower the risk of fractures, particularly in individuals who are deficient. Cod liver oil also contains omega-3 fatty acids, which may have anti-inflammatory effects and could potentially benefit bone health, though evidence in this area is less robust.

However, the direct evidence supporting cod liver oil specifically (as opposed to isolated vitamin D supplementation) for osteoporosis is limited. Most clinical trials focus on vitamin D and calcium, not cod liver oil as a whole product. Furthermore, excessive intake of vitamin A, also present in cod liver oil, has been associated with increased fracture risk in some studies. Thus, while cod liver oil provides nutrients important for bone health and there is a mechanistic basis for its use, the overall quality and quantity of direct evidence is moderate, justifying a rating of 3/5.

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Other ingredients used for Osteoporosis

7-hydroxymatairesinol (HMR)
8-Prenylnaringenin
Abalone
Acacetin
Alfalfa
algal oil
Algal protein
Algalin
Algas calcareas
alpha-ketoglutarate (AKG)
AMP-activated protein kinase (AMPK)
ampelopsin
animal protein
animal Tissue
anthocyanins
antler
apigenin
arctiin
ashwagandha
astragalin
astragaloside
astragalus
barrenwort
beta caryophyllene
biochanin
blueberry
bok choy
bone protein
boron
bovine
bovine protein
broccoli
calcium
calycosin
catechins
caterpillar mushroom
Chinese Ligustrum berry
Cissus quadrangularis
cistanche
cod liver oil
collagen
collard
conjugated linoleic acid (CLA)
curcumin
cyanidin
daidzein
DHEA
DHEA (dehydroepiandrosterone)
dioscorea
diosgenin
diosmetin
DPA (docosapentaenoic acid)
Drynaria
ecdysteroids
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
epicatechin
equol (proprietary)
estrogen
Eucommia ulmoides
fern
fish
fish protein
flavanols
flavanones
flavans
flavones
fo-ti
formononetin
genistein
genistin
glycitin
goji berry
gooseberry
haliotis
hesperetin
hesperidin
horsetail
Hyperoside
icariin
ipriflavone
isoflavones
Kaempferol
kale
knotweed
Legume protein
Lentinula edodes mycelia
lignans
Lithothamnion
Lycium
maca
magnesium
manganese
Marine protein
Microcrystalline hydroxyapatite concentrate (MCHC)
Milk Protein
Mineral blend
Naringenin
Neoeriocitrin
olive
omega-3 fatty acids
paeoniflorin
Phaeophyceae
phosphorus
Phytoecdysteroid
Phytoestrogens
polymethoxylated flavones
polysaccharides
polyunsaturated fat
pomegranate
proanthocyanidins
procyanidin
prune
Puerarin
quercetin
red clover
Rehmannia
rehmannia glutinosa
resveratrol
royal jelly
rutin
seaweed
sesame
Shilajit
silica
silicon
Soy
soy isoflavones
Soy Protein
soybean
specialized pro-resolving mediators (SPMs)
Stilbenoid
strontium
tocotrienols
Ursolic Acid
Vegetable Protein
vitamin C
vitamin D
vitamin D3
vitamin K
Wakame
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Xanthophyll
Zinc

Products containing cod liver oil