Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Streptococcus salivarius is a commensal bacterium commonly found in the human oral cavity and upper respiratory tract. In the context of oral surgery, its use is based on a growing body of scientific evidence supporting its role as a probiotic to help maintain oral health, prevent postoperative infections, and support the re-establishment of a balanced oral microbiota after surgical procedures. Several clinical studies have investigated the administration of specific S. salivarius strains (notably K12 and M18) post-operatively, reporting reduced incidence of oral pathogens such as Streptococcus pyogenes and Streptococcus mutans, as well as decreased risk of secondary infections and oral malodor. S. salivarius produces bacteriocins (e.g., salivaricin A and B), which inhibit the growth of pathogenic bacteria implicated in dental caries and postoperative infections. Systematic reviews and randomized controlled trials (RCTs) show moderate evidence for reduced infection rates and improvement in oral health markers after dental procedures when S. salivarius probiotics are used adjunctively. However, the strength of the evidence is limited by small sample sizes, heterogeneity in study design, and variation in surgical procedures studied. Overall, the scientific rationale for using S. salivarius in oral surgery is supported by moderate-quality clinical evidence, though further large-scale studies are needed to confirm its efficacy and optimal administration protocols.

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