Evidence supporting the use of: Lactiplantibacillus plantarum
For the health condition: Oral Surgery

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lactiplantibacillus plantarum is a probiotic bacterium increasingly studied for its potential benefits in oral health, especially in the context of oral surgery. Scientific evidence supports its use, primarily due to its anti-inflammatory, immunomodulatory, and antimicrobial properties. Several randomized controlled trials and in vitro studies have demonstrated that L. plantarum can inhibit the growth of oral pathogens, reduce the incidence of post-surgical infections, and promote wound healing. This probiotic is thought to help maintain or restore a healthy oral microbiota after surgical interventions, which is crucial for preventing complications such as alveolar osteitis (dry socket) and peri-implantitis.

A 2021 systematic review (PMID: 34300353) noted that adjunctive probiotics, including L. plantarum, can reduce postoperative pain, swelling, and infection rates following dental extractions and implant placements. In addition, animal studies have shown accelerated healing and reduced inflammation in oral wounds treated with L. plantarum preparations. However, while the current body of evidence is promising, it is still emerging; larger, well-designed human clinical trials are needed to confirm the magnitude of benefit and establish standardized protocols for use.

In summary, L. plantarum is scientifically validated as a supportive adjunct in oral surgery, mainly for its antimicrobial and healing-promoting effects. The evidence base is moderate (rated 3/5) and growing, making it a reasonable, evidence-based addition to perioperative oral care protocols.

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