Evidence supporting the use of: Hydrogen peroxide
For the health condition: Oral Surgery

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Hydrogen Peroxide in Oral Surgery: Scientific Evidence Overview

Hydrogen peroxide (H2O2) has been utilized in dental and oral surgery settings primarily as an antiseptic and oral debriding agent. Its use is supported by scientific evidence, though its efficacy and safety are subject to concentration and application protocol.

Hydrogen peroxide is valued for its ability to release oxygen upon contact with tissue, which helps mechanically debride wounds and reduce microbial load. Several studies have demonstrated its effectiveness in reducing bacterial contamination and aiding in the cleaning of oral wounds post-surgery. For example, it is commonly used as a mouth rinse after procedures such as tooth extraction to promote oral hygiene and reduce the risk of infection.

However, evidence for hydrogen peroxide’s superiority over other antiseptics is mixed. Some clinical trials have shown modest benefits in wound healing and plaque reduction, while others have found no significant difference compared to saline or chlorhexidine. Concerns have been raised about its cytotoxic potential at higher concentrations (>3%), which may delay wound healing or irritate oral tissues.

In summary, while hydrogen peroxide has a scientific basis for use in oral surgery as an antiseptic and debriding agent, the strength of evidence supporting its routine use is moderate. Its use is generally considered safe at low concentrations (1.5-3%) for short-term application, but alternatives may be preferred for certain patients or procedures.

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Products containing Hydrogen peroxide

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