Evidence supporting the use of: Coenzyme Q10 (CoQ10)
For the health condition: Oral Surgery

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Coenzyme Q10 (CoQ10) is an antioxidant and a key component of mitochondrial energy production. In the context of oral surgery, its use is somewhat supported by scientific evidence, though the level of support is modest (rated 2 out of 5). Several studies have investigated the potential benefits of CoQ10 in oral health, particularly in periodontal (gum) disease, due to its antioxidant, anti-inflammatory, and tissue-healing properties. A handful of small clinical trials and animal studies have suggested that topical or systemic CoQ10 may help reduce inflammation and promote healing in oral tissues post-surgery. For example, CoQ10 has been shown to decrease markers of oxidative stress and improve healing in gingival tissues following dental procedures. However, these studies are generally small, and some have methodological limitations.

There is also some evidence that CoQ10 supplementation can improve recovery and healing after oral surgical procedures, such as extractions or implant placements, due to its influence on cellular energy metabolism and its ability to counteract oxidative damage. Despite these potential benefits, CoQ10 is not a standard part of oral surgery protocols and is more often used adjunctively, especially in patients with underlying deficiencies or increased oxidative stress. Larger, high-quality randomized controlled trials are needed to firmly establish its efficacy and optimal usage in oral surgery. In summary, while there is a scientific rationale and some preliminary evidence supporting CoQ10 in oral surgery, its use is not yet strongly validated.

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