Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Vitamin A is scientifically validated as an essential nutrient for vision, particularly for the prevention and treatment of night blindness (nyctalopia). Night blindness is often caused by a deficiency of vitamin A, which is crucial for the synthesis of rhodopsin—a light-sensitive protein in the retina necessary for vision in low-light conditions. The connection between vitamin A deficiency and impaired night vision was established in the early 20th century and further elucidated through biochemical and clinical studies. Supplementation with vitamin A has been consistently shown to reverse night blindness due to deficiency. The World Health Organization (WHO) and multiple clinical guidelines recommend vitamin A supplementation in populations at risk of deficiency, particularly in children and pregnant women, both to prevent and treat night blindness. Randomized controlled trials, epidemiological data, and case studies all provide robust evidence for the efficacy of vitamin A in this context. In summary, the use of vitamin A for night blindness is supported by strong scientific evidence, with a clear understanding of the underlying mechanism, and is a standard medical intervention in cases of deficiency.

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