Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin B1, also known as thiamine, has scientific support for its use in the management of certain types of neuralgia and neuritis, particularly when these conditions are related to thiamine deficiency. Thiamine is essential for normal nerve function, as it is a coenzyme in carbohydrate metabolism and is involved in the production of neurotransmitters. Deficiency of thiamine can lead to neurological disorders such as beriberi and Wernicke-Korsakoff syndrome, both of which involve nerve inflammation and neuropathic symptoms.

Clinical studies, particularly from mid-20th century, demonstrated that supplementation with thiamine could improve symptoms in patients with peripheral neuropathy and neuritis caused by deficiency. More recently, combinations of B vitamins (B1, B6, B12) have been shown in some studies to reduce neuropathic pain, though isolating the specific effect of thiamine itself can be challenging. Thiamine supplementation is widely used as standard therapy for neuropathies associated with alcoholism, malnutrition, or other causes of deficiency.

However, for neuralgia or neuritis unrelated to deficiency (such as idiopathic trigeminal neuralgia or autoimmune neuritis), the evidence for benefit is limited. While B vitamins are often used in practice for neuropathic pain, robust clinical trials for thiamine’s efficacy in these cases are lacking, and benefit is principally established where deficiency is present.

More about Vitamin B1
More about Neuralgia and Neuritis

Other ingredients used for Neuralgia and Neuritis

Other health conditions supported by Vitamin B1

Products containing Vitamin B1