Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Dodeca-2E,4E-dienoic acid isobutylamide is a primary alkamide constituent found in Echinacea species, particularly Echinacea angustifolia and Echinacea purpurea. Traditionally, certain Native American groups and later herbal practitioners used echinacea preparations for various ailments, including pain conditions described as "nerve pain" or "tingling," which could encompass neuralgia and neuritis. These uses were based on empirical observations and the plant's reputed anti-inflammatory and analgesic properties.

However, while there is some preclinical evidence that alkamides from echinacea may interact with cannabinoid receptors and modulate immune responses, there is a lack of robust, direct scientific evidence supporting the use of dodeca-2E,4E-dienoic acid isobutylamide or echinacea extracts in the treatment of neuralgia or neuritis in humans. Clinical studies have generally focused on echinacea’s immunomodulatory effects, especially for upper respiratory tract infections, not on neuropathic pain conditions. Any current use for neuralgia or neuritis is thus best characterized as traditional and based on historical herbal practices rather than validated by modern scientific research.

In summary, the application of dodeca-2E,4E-dienoic acid isobutylamide for neuralgia and neuritis is rooted in traditional medicine, with limited and indirect scientific rationale for its efficacy in these specific conditions.

More about Dodeca-2E, 4E-Dienoic Acid Isobutylamide
More about Neuralgia and Neuritis

Other ingredients used for Neuralgia and Neuritis

Other health conditions supported by Dodeca-2E, 4E-Dienoic Acid Isobutylamide

Products containing Dodeca-2E, 4E-Dienoic Acid Isobutylamide