Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Spikenard (Nardostachys jatamansi) has a long history of use in traditional medicine systems, particularly in Ayurveda and Traditional Chinese Medicine, as a calming agent for the nervous system. Historically, it has been used to treat conditions described as “nervous exhaustion,” which may encompass symptoms such as fatigue, anxiety, insomnia, and mental stress. The traditional rationale is based on its reputed sedative, anxiolytic, and adaptogenic effects, with preparations of the root or essential oil being used to promote relaxation and restore balance to the mind and body.

While laboratory studies have begun to investigate the neuropharmacological properties of spikenard, including its potential to modulate neurotransmitters and reduce anxiety in animal models, there is a lack of robust clinical trials in humans to confirm efficacy for nervous exhaustion per se. Therefore, its use for this condition is primarily justified by traditional knowledge and anecdotal reports rather than strong scientific validation. The evidence rating of 2 reflects the presence of preliminary scientific exploration and extensive traditional use, but insufficient clinical evidence to support high confidence in its effectiveness for nervous exhaustion.

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