Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Panax ginseng, commonly known as ginseng, has a long-standing history in traditional Chinese medicine as an adaptogen—an agent believed to help the body resist physical, chemical, and biological stressors. In historical texts, ginseng is described as a tonic for "Qi" (vital energy) depletion, fatigue, and weakness, which aligns with the concept of "nervous exhaustion" in Western herbal traditions. It was and is still used to restore vitality, improve mental and physical performance, and promote overall resilience to stress.

While modern research has explored ginseng’s effects on fatigue and cognitive function, most clinical trials focus on general fatigue, chronic fatigue syndrome, or stress-induced fatigue, rather than "nervous exhaustion" as a discrete diagnosis. Some studies suggest that ginseng may enhance mental performance, reduce subjective feelings of fatigue, and modulate the stress response, possibly through effects on the hypothalamic-pituitary-adrenal (HPA) axis and neurotransmitter regulation. However, the quality and consistency of evidence are moderate, and many studies have limitations such as small sample sizes or methodological weaknesses.

Therefore, the use of Panax ginseng for "nervous exhaustion" is primarily justified by traditional use, with moderate support from scientific studies relating to fatigue and stress, but not specifically for "nervous exhaustion" as a medical category.

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