Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Deer Root (sometimes referring to Leonurus cardiaca or Prenanthes alba, but commonly known as White Lettuce or Lion’s Foot) has a history of use in North American Indigenous herbal medicine and traditional Western herbalism. Its use for nervous exhaustion—characterized by fatigue, anxiety, and nervous agitation—comes mainly from traditional sources. Herbalists in the 19th and early 20th centuries recommended Deer Root as a mild nervine and tonic, suggesting it could help with symptoms of nervous disorders, weakness, and overwork. However, there is little to no modern clinical or pharmacological research validating its efficacy or mechanism for this purpose. The evidence is primarily anecdotal, drawn from ethnobotanical records and early herbal literature. No significant controlled studies or peer-reviewed research confirm its safety or effectiveness for nervous exhaustion. Therefore, while it has a traditional basis for use in this context, the strength of evidence is weak, reflecting the absence of rigorous scientific validation.

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