Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Gamma Linolenic Acid (GLA) is an omega-6 fatty acid found in oils such as evening primrose, borage, and blackcurrant seed oil. Its use to support the nerves, particularly in the context of peripheral neuropathy, is supported by some scientific evidence. Several clinical studies have investigated GLA supplementation in individuals with diabetic neuropathy. For example, a randomized controlled trial by Keen et al. (1993) demonstrated that GLA supplementation improved nerve function in diabetic patients over the course of a year. Other studies have shown improvements in symptoms such as numbness, tingling, and pain in people with mild diabetic neuropathy, especially in those with good glycemic control.

The proposed mechanism is that GLA is converted in the body to dihomo-gamma-linolenic acid (DGLA), which can be further metabolized to anti-inflammatory prostaglandins, potentially reducing nerve inflammation and supporting nerve function. However, while these results are promising, the overall quality and number of studies are limited, and some systematic reviews note that more rigorous trials are necessary to confirm efficacy and determine optimal dosing. GLA is not generally recommended as a first-line treatment for neuropathic conditions, but may be considered as an adjunct in certain cases.

In summary, there is scientific evidence, though moderate in strength, supporting the use of GLA for nerve health—particularly in diabetic neuropathy. However, the evidence is not definitive, and further studies are warranted.

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