Evidence supporting the use of: Vitamin B1 (Thiamine)
For the health condition: Nerve Damage
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Vitamin B1 (Thiamine) has a scientifically supported role in the treatment and support of certain types of nerve damage, particularly those related to thiamine deficiency. Thiamine is essential for normal nerve function due to its involvement in glucose metabolism and neurotransmitter synthesis. Deficiency in thiamine can lead to neuropathies such as beriberi and Wernicke-Korsakoff syndrome, both of which involve significant nerve damage.
Clinical studies and case reports robustly demonstrate that supplementation with thiamine can reverse or halt progression of neuropathic symptoms in patients with confirmed deficiency. For example, in alcoholic patients or those with malnutrition, thiamine supplementation is standard of care for preventing and treating neuropathic complications. Additionally, some evidence suggests that thiamine and its fat-soluble derivative, benfotiamine, may have benefits for diabetic neuropathy by reducing oxidative stress and improving nerve conduction, though results are mixed and more research is needed in non-deficiency contexts.
Overall, while the evidence is strongest for thiamine’s efficacy in deficiency-related neuropathies, there is a moderate level of scientific support for its use in other types of nerve damage, particularly diabetic neuropathy. The use of thiamine for supporting nerve health is therefore justified by scientific evidence, particularly when deficiency is present.
Other ingredients used for Nerve Damage
Acetyl L-carnitineastaxanthin
biotin
coenzyme Q10 (CoQ10)
turmeric
fish protein
l-carnitine
L-glutathione
L-taurine
Lentinula edodes mycelia
lion's mane
magnesium
medium chain triglycerides (MCT)
nicotinamide riboside
omega-3 fatty acids
phospholipids
rutin
specialized pro-resolving mediators (SPMs)
Thiamin (vitamin B1)
ubiquinol
vitamin B12
vitamin B6
vitamin D
vitamin E
zinc
7,8-Dihydroxyflavone
animal Tissue
antler
apigenin
Agmatine
alpha-lipoic acid
Algal protein
benfotiamine
cocarboxylase
cannabidiol
Dimethyl sulfoxide (DMSO)
Epidermal Growth Factor
elk antler
frankincense
hericium mushroom
Indian pipe
Lycium
lysophosphatidic acid
Methylcobalamin
Puerain
pyrroloquinoline quinone
Pycnogenol
Palmitoylethanolamide (PEA)
Salidroside
Taurine
Tetrahydropalmatine
Xanthophyll
Other health conditions supported by Vitamin B1 (Thiamine)
AlcoholismAnorexia
Burning Feet or Hands
Cardiovascular Disease
Cirrhosis of the Liver
Depression
Diabetes
Digestion (poor)
Fatigue
Heart (weakness)
Memory and Brain Function
Nerve Damage
Peripheral Neuropathy