Evidence supporting the use of: Rubiaceae (unspecified)
For the health condition: Nausea and Vomiting

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

The use of plants from the Rubiaceae family to manage nausea and vomiting is primarily rooted in traditional medicine rather than being scientifically validated. Several genera within Rubiaceae, such as Coffea (coffee), Morinda (noni), and Uncaria (cat’s claw), have been used in various ethnomedical contexts for digestive issues, including nausea and vomiting. For example, Morinda citrifolia (noni) fruit juice has been traditionally used in Polynesian medicine to alleviate gastrointestinal discomfort, including symptoms like nausea. Similarly, in some regions, decoctions made from the roots or leaves of Rubiaceae plants are employed as general digestive aids. However, these uses are largely anecdotal and are not supported by robust clinical trials or experimental studies.

The evidence supporting the effectiveness of Rubiaceae species for treating nausea and vomiting is limited to ethnobotanical reports, with few, if any, controlled studies investigating mechanisms or efficacy. Modern pharmacological research has focused more on the anticancer, antioxidant, or anti-inflammatory properties of Rubiaceae members, leaving their purported antiemetic properties largely unexplored. As such, while there is clear historical and traditional support for the use of certain Rubiaceae plants in managing nausea and vomiting, scientific validation is lacking, and the evidence strength is low.

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