Wheat germ is sometimes promoted for supporting nail health primarily due to its rich nutrient profile, especially its high content of vitamin E, B vitamins (such as biotin), zinc, and essential fatty acids. These nutrients are known to play roles in maintaining healthy skin, hair, and nails. Scientific evidence supporting the use of wheat germ specifically for nail health is limited but plausible, as deficiencies in biotin, zinc, and vitamin E have been associated with brittle or unhealthy nails. Several small studies have suggested that biotin supplementation can improve nail strength and thickness, and wheat germ is a natural source of this vitamin. However, most clinical research uses isolated supplements rather than wheat germ itself, and direct studies on wheat germ for nail health are lacking.

Historically, wheat germ has been valued as a nutritious food since the early 20th century, and some traditional health practitioners have recommended it for general strengthening of hair and nails due to its nutrient density. Nevertheless, recommendations are typically extrapolated from its overall nutritional value rather than from direct clinical trials. In summary, while the use of wheat germ for supporting nail health is grounded in scientific rationale regarding its nutrient content, there is only limited direct scientific validation, and evidence is stronger for specific nutrients found in wheat germ than for wheat germ itself.