Evidence supporting the use of: Rhaponticum
For the body system: Muscles
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Rhaponticum (commonly Rhaponticum carthamoides, also known as Leuzea or Maral root) has a history of traditional use in Russia and Central Asia for enhancing physical performance and supporting muscle strength. More importantly, its use as a muscle-supportive botanical has been partially validated by scientific research. The primary active compounds in Rhaponticum are phytoecdysteroids (notably 20-hydroxyecdysone), which are steroid-like molecules found in plants. Several animal and in vitro studies suggest that these ecdysteroids can stimulate protein synthesis in skeletal muscle cells, potentially enhancing muscle growth and recovery. Some human studies, though limited in number and size, have reported improvements in muscle mass and athletic performance metrics with Rhaponticum extract supplementation. These effects are thought to occur without the androgenic side effects associated with anabolic steroids.
However, the body of human clinical evidence remains small, with most data coming from Eastern European research, some of which is not easily accessible or published in high-impact journals. Therefore, while there is a plausible scientific rationale and some supporting evidence, the overall quality and quantity of human research is still moderate. Thus, the evidence for Rhaponticum’s support of the muscle body system can be considered as partially validated by science, but further rigorous, large-scale clinical trials are warranted.
Other ingredients that support Muscles
acetyl l-carnitineadenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
astaxanthin
beet
beta-alanine
bovine
bovine liver
branched-chain amino acids
bromelain
caffeine
calcium
cherry
chloride
coenzyme Q10 (CoQ10)
colostrum
conjugated linoleic acid (CLA)
cordyceps
creatine monohydrate
turmeric
d-alpha tocopherol
devil's claw
dong quai root
fish protein
forskohlii root
l-isoleucine
iron
kale
l-alanine
l-alanyl-l-glutamine
l-arginine
l-carnitine
l-carnosine
l-citrulline
l-glutamine
l-glycine
l-leucine
l-ornithine
l-proline
l-taurine
l-threonine
l-valine
magnesium
malic acid
maltodextrin
maltose
methylsulfonylmethane (MSM)
milk
nicotinamide riboside
ornithine alpha-ketoglutarate
peppermint oil
phosphorus
phytocannabinoids
potassium
protein
quinoa
rhizome
sardines
black ginger
soybean
specialized pro-resolving mediators (SPMs)
spinach
spirulina
tongkat ali
ubiquinol
Urolithin A
vitamin B
vitamin C
vitamin D
vitamin D3
water
watermelon
whey protein
white willow
β-nicotinamide mononucleotide (NMN)
suma
squawvine
sodium salt
solomon's seal
siler root
eucommia
electrolytes blend (proprietary)
guelder rose
polyphenols
trace minerals
wintergreen
camphor oil
menthol oil
wheat germ
wood betony
herbal blend (proprietary)
algae
chickpea protein
brown rice protein
AMP-activated protein kinase (AMPK)
arnica
17 alpha methyl 17 beta hydroxy 5 alpha androst 2 ene
17a-di methyl-bol
11-Ketotestosterone
2, 17a-dimethyl-17b-hydroxy-5a-androstan-1-ene-3-one
2a, 17a-dimethyl-17b-hydroxy-5a-androstan-3-one
Arginine Alpha Ketoglutarate
Animal Tissue
Antler
Arginine Creatine
Arginine nitrate
Arachidonic Acid
Arginine malate
Arginine aspartate
Avocado
Anserina
Alpha-ketoisocaproic acid
Acetylcholine
adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
Arginine alpha-ketoisocaproate
Arginine silicate
Animal protein
Blue Cohosh
Biopeptide
Beta-hydroxybutyrate
Bicarbonate
Beef Protein
Black galingale
Beef
Beef liver
Bovine Protein
Black Gram
Black willow
Ba Ji Tian
Bee products
banana
BCAA
Chia seed
Casein
Cardarine
Chinese Mountain Ant
Carnosine
Citrate malate
Cyathula
Curcuminoid
Cramp Bark
Chuchuhuasi
Cyanotis Vaga
Coca
Coconut Water
Cetylated Fatty Acids
Creatine
Chicken
Curcuma
C-Phycocyanin
Cyanotis arachnoides
DL-Methionine
Deer Velvet
Date
D-Ribose
Dextrose
Dimethyl sulfoxide (DMSO)
Dipsacus
Dipeptide
epicatechin
Epistane
Egg
Erythrina
Elk antler
Eurycoma Longifolia
Emu Oil
Ecdysteroids
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
Essential Oil Blend
Egg protein
Fish
Fatty acids
fibroblast growth factor
Guanidinoacetic acid
Ginsenosides
Glutamine
GMS-ribose
glucose
Glycocyamine
Glycerol
Glycine
Guanidinopropionic Acid (GPA )
Isoleucine
Milk Protein
Phosphate Salt
Potash
Quinoa Protein
Shellfish
salt
Soy Protein
Tribulus Terrestris
Other body systems supported by Rhaponticum
Adrenal CortexAdrenal Glands
Circulatory System
Glandular System
Immune System
Male Reproductive System
Muscles
Reproductive System
Testes