Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Polyphenols are a group of naturally occurring compounds found in plants, with abundant sources including fruits, vegetables, tea, coffee, and cocoa. Recent scientific studies suggest that polyphenols may have beneficial effects on muscle health and function. Research has focused particularly on their antioxidant and anti-inflammatory properties, which may help reduce exercise-induced muscle damage and enhance recovery. For example, certain polyphenols like quercetin, resveratrol, and epigallocatechin gallate (EGCG) have been shown in animal and some human studies to improve muscle performance, reduce markers of oxidative stress, and decrease delayed onset muscle soreness (DOMS) after exercise.

Additionally, there is emerging evidence that polyphenols may support mitochondrial biogenesis and muscle protein synthesis, both important for muscle maintenance and growth. However, while several small-scale human trials have demonstrated positive effects, the overall body of evidence remains moderate, with some studies not finding significant benefits. Most research has been conducted on isolated polyphenols or polyphenol-rich extracts rather than on polyphenols as a broad group. More rigorous, large-scale human clinical trials are needed to firmly establish their efficacy in supporting the muscle system.

Overall, while the scientific basis for polyphenols’ role in muscle health is promising and growing, it is not yet definitive. The evidence currently supports a moderate rating.

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Products containing polyphenols

Nature's Sunshine Grapine With Protectors (SynerPro)
Nature's Sunshine Super ORAC
Nature's Sunshine Super Trio