Synopsis

Source of validity: Scientific
Rating (out of 5): 2

L-proline is a non-essential amino acid that plays a role in the biosynthesis of proteins, particularly collagen, which is abundant in connective tissues such as tendons, ligaments, and skin. The scientific rationale for supporting the muscle system with L-proline primarily relates to its role in collagen synthesis, which is crucial for the structural integrity of connective tissue associated with muscles. Some in vitro and animal studies suggest that L-proline availability can influence collagen production, potentially aiding in tissue repair and recovery following muscle injury or strenuous exercise.

However, direct evidence in humans for L-proline supplementation specifically enhancing muscle health, function, or recovery is limited. Most healthy adults obtain sufficient proline from their diet and endogenous synthesis, and there is little evidence that supplementation provides additional benefit in the context of muscle strength or mass. While L-proline is sometimes included in sports nutrition products or supplements marketed for joint and muscle support, robust clinical trials demonstrating clear benefits in muscle function or recovery are lacking. Thus, the scientific evidence supporting L-proline supplementation for muscle health is weak (rated 2/5), and its use is more theoretical based on its biochemical role rather than proven clinical outcomes.

More about l-proline
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Other ingredients that support Muscles

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Products containing l-proline

Nature's Sunshine Free Amino Acids
Nature's Sunshine Target TS-II Formula
Nature's Sunshine VitaWave