Evidence supporting the use of: Creatine
For the body system: Muscles
Synopsis
Source of validity: Scientific
Rating (out of 5): 5
Creatine is one of the most extensively studied dietary supplements for supporting muscle health and performance. Scientific research strongly supports its use for enhancing muscle strength, power output, and lean body mass, particularly in the context of resistance training and high-intensity exercise. Creatine works primarily by increasing the phosphocreatine stores in muscle tissue, which in turn replenishes ATP (adenosine triphosphate), the primary energy currency during short, explosive movements.
Numerous randomized controlled trials and meta-analyses have demonstrated that creatine supplementation leads to significant improvements in muscular strength, sprint performance, and muscle hypertrophy. The International Society of Sports Nutrition (ISSN) and other authoritative bodies have concluded that creatine is both safe and effective for most healthy adults when used as directed.
While creatine is naturally present in certain foods (such as red meat and fish), supplementation can further increase muscle phosphocreatine content, especially in individuals with low dietary intake. Its popularity is not just a result of tradition or anecdotal reports; rather, it is underpinned by robust scientific validation accumulated over decades of research. There is also evidence suggesting that creatine may aid in muscle recovery and reduce the risk of certain injuries.
In summary, creatine’s use for supporting the muscular system is justified by strong scientific evidence, with a high degree of consensus in the scientific and sports performance communities regarding its efficacy and safety.
Other ingredients that support Muscles
acetyl l-carnitineadenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
astaxanthin
beet
beta-alanine
bovine
bovine liver
branched-chain amino acids
bromelain
caffeine
calcium
cherry
chloride
coenzyme Q10 (CoQ10)
colostrum
conjugated linoleic acid (CLA)
cordyceps
creatine monohydrate
turmeric
d-alpha tocopherol
devil's claw
dong quai root
fish protein
forskohlii root
l-isoleucine
iron
kale
l-alanine
l-alanyl-l-glutamine
l-arginine
l-carnitine
l-carnosine
l-citrulline
l-glutamine
l-glycine
l-leucine
l-ornithine
l-proline
l-taurine
l-threonine
l-valine
magnesium
malic acid
maltodextrin
maltose
methylsulfonylmethane (MSM)
milk
nicotinamide riboside
ornithine alpha-ketoglutarate
peppermint oil
phosphorus
phytocannabinoids
potassium
protein
quinoa
rhizome
sardines
black ginger
soybean
specialized pro-resolving mediators (SPMs)
spinach
spirulina
tongkat ali
ubiquinol
Urolithin A
vitamin B
vitamin C
vitamin D
vitamin D3
water
watermelon
whey protein
white willow
β-nicotinamide mononucleotide (NMN)
suma
squawvine
sodium salt
solomon's seal
siler root
eucommia
electrolytes blend (proprietary)
guelder rose
polyphenols
trace minerals
wintergreen
camphor oil
menthol oil
wheat germ
wood betony
herbal blend (proprietary)
algae
chickpea protein
brown rice protein
AMP-activated protein kinase (AMPK)
arnica
17 alpha methyl 17 beta hydroxy 5 alpha androst 2 ene
17a-di methyl-bol
11-Ketotestosterone
2, 17a-dimethyl-17b-hydroxy-5a-androstan-1-ene-3-one
2a, 17a-dimethyl-17b-hydroxy-5a-androstan-3-one
Arginine Alpha Ketoglutarate
Animal Tissue
Antler
Arginine Creatine
Arginine nitrate
Arachidonic Acid
Arginine malate
Arginine aspartate
Avocado
Anserina
Alpha-ketoisocaproic acid
Acetylcholine
adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
Arginine alpha-ketoisocaproate
Arginine silicate
Animal protein
Blue Cohosh
Biopeptide
Beta-hydroxybutyrate
Bicarbonate
Beef Protein
Black galingale
Beef
Beef liver
Bovine Protein
Black Gram
Black willow
Ba Ji Tian
Bee products
banana
BCAA
Chia seed
Casein
Cardarine
Chinese Mountain Ant
Carnosine
Citrate malate
Cyathula
Curcuminoid
Cramp Bark
Chuchuhuasi
Cyanotis Vaga
Coca
Coconut Water
Cetylated Fatty Acids
Creatine
Chicken
Curcuma
C-Phycocyanin
Cyanotis arachnoides
DL-Methionine
Deer Velvet
Date
D-Ribose
Dextrose
Dimethyl sulfoxide (DMSO)
Dipsacus
Dipeptide
Egg
Elk antler
Emu Oil
Ecdysteroids
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
Egg protein
Glycine
Isoleucine
Milk Protein
Phosphate Salt
Potash
Quinoa Protein
salt
Soy Protein